Effect of surfactant head group on micelle structure of drug containing micelles


The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms in solution, and the drug molecules that its aggregate(s) can incorporate. Once this understanding is gain is should be possible to rationalise the design of surfactant-based nanosized colloidal drug delivery systems (such as micelles) and thence to optimize their drug loading. The results of the study will be essential in aiding the rational selection of surfactant micelle to dissolve a particular drug.

DOI https://doi.org/10.5286/ISIS.E.24089862
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24089862
Creator Professor Jayne Lawrence; Dr Dave Barlow; Mr Yussif Saaka; Professor Gino Martini; Dr Prashant Balani
Publisher ISIS Neutron and Muon Source
Publication Year 2015
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2012-11-22T08:57:11Z
Temporal Coverage End 2012-11-26T08:53:29Z