26 datasets found

Evaluation of the impact of the drug PP50 on the filamentation process at 37°C for different times on C. albicans SC5314 strain, 0h, 5h and 10h and at different concentrations...

In recent years nano- and microparticles composed of polymeric or lipid material have been proposed as drug carriers. Their use allows the modification of the biopharmaceutic...

The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles...

Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel...

Hydrophobic drug encapsulation is one of the widely used strategies to overcome the poor adsorption and bioavailability of these drugs in vivo. Water-soluble amphiphilic...

The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the...

Despite interest in microemulsions as drug delivery vehicles, there is a lack of structural understanding to justify the formulations used. The present study examines the use of...

A Unilever proprietary technology has been shown to inhibit biofilm growth and development, and is also found to possess antimicrobial activity, effective both as a...

The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

In a pharmaceutical industry context, hydrophilic polymeric matrices are a popular methodology for extending the release of drugs. However, issues sometimes arise -...

The formation of stable particle dispersions are essential to the success of a wide range of commercial products from inks, paints and foodstuffs to cosmetic and pharmaceutical...

Complex polymer architectures such as comb polymers have been studied for their highly customisable chemical properties. Potential applications have been identified in a wide...

Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

Abstract. In experiments at LLB and ILL we have measured low-resolution INS spectra and elastic scans for H2O- and D2O-hydrated samples of a 15-residue oligopeptide between 30...

This project concerns fundamental and strategically important research underlying the development of new drug delivery vehicles. We propose to sample phase diagram of...

Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a...

Nanoemulsions have considerable potential for dermatological drug delivery. Small angle neutron scattering in combination with contrast variation will be used to characterize...

Micro-/nano- thermosensitive microgels are paramount in Nanomedicine, as they support a multifunctional approach for diseases treatment (localization and simultaneous controlled...