26 datasets found

Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the...

Although microemulsions have been widely investigated as potential drug delivery vehicles, relatively little work has been performed establishing the detailed molecular...

Controlled drug delivery must be supported by specialized multi-task devices for addressing a predetermined therapeutic dose in controlled physiological conditions. Combining...

The proposal seeks to investigate the structure and hydration of the nootropic drug piracetam in aqueous solutions by neutron scattering on the SANDALS instrument, with...

Bio-responsive polymers hold great promise as delivery vehicles for drugs, peptides and proteins as their chemistry can be tuned to effect a change in physico-chemical...

The pharmaceutical industry has been described as being 'in a period of crisis' as the number of drug approvals relative to most major pharmaceutical companies Research and...

Micro-/nano- thermosensitive microgels are paramount in Nanomedicine, as they support a multifunctional approach for diseases treatment (localization and simultaneous controlled...

Nanoemulsions have considerable potential for dermatological drug delivery. Small angle neutron scattering in combination with contrast variation will be used to characterize...

Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a...

This project concerns fundamental and strategically important research underlying the development of new drug delivery vehicles. We propose to sample phase diagram of...

Abstract. In experiments at LLB and ILL we have measured low-resolution INS spectra and elastic scans for H2O- and D2O-hydrated samples of a 15-residue oligopeptide between 30...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel...

Complex polymer architectures such as comb polymers have been studied for their highly customisable chemical properties. Potential applications have been identified in a wide...

The formation of stable particle dispersions are essential to the success of a wide range of commercial products from inks, paints and foodstuffs to cosmetic and pharmaceutical...

In a pharmaceutical industry context, hydrophilic polymeric matrices are a popular methodology for extending the release of drugs. However, issues sometimes arise -...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms...

A Unilever proprietary technology has been shown to inhibit biofilm growth and development, and is also found to possess antimicrobial activity, effective both as a...

Despite interest in microemulsions as drug delivery vehicles, there is a lack of structural understanding to justify the formulations used. The present study examines the use of...