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Surface adsorption of lipopeptides: interfacial layer structure
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Microemulsion formulations for local anaesthesia
Although microemulsions have been investigated as potential drug delivery vehicles, little work has been performed establishing the detailed molecular architecture of the... -
The impact of polyelectrolytes on surfactant adsorption onto cellulose surfaces
Studying surfactant and mixed surfactant adsorption on model solid surfaces, which mimic real surfaces such as fabrics, hair and skin, is starting to provide a real insight into... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
Polymer-surfactant adsorption at the oil-water interface
Polymer-surfactant stabilised emulsion droplets are a potentially exciting route for micro-encapsulation of volatile agents (such as perfumes, flavours and many other benefit... -
Effect of structure on the location of hydrophobic drugs in ionic surfactant ...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of... -
Novel block bottlebrush polyelectrolytes: The effect of cationic block charge...
In this work we will study a novel block copolymers consisting of a linear cationic block and uncharged bottle-brush block having 45 units long poly(ethylene oxide) side chains.... -
Interaction of keratin with surfactants studied by SANS
This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using... -
Polymer conjugates for drug delivery
Complex polymer architectures such as comb polymers have been studied for their highly customisable chemical properties. Potential applications have been identified in a wide... -
Using polymer / surfactant mixtures to optimise / enhance perfume delivery to...
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
Resolving the enigma of self-assembled meso-structures in an H-bonding rich m...
In a recent successful LOQ experiment (RB 1810629), we have unexpectedly observed possible multilayer stacking of sodium dodecyl sulfate (SDS; ~2wt%) bilayers in glycerol... -
On the peculiarities of the structure of particle stabilised foam
Many formulated products pass through or end up as foams, comprising immiscible millimeter sized bubbles dispersed into an aqueous continuous phase. Frequently, surfactants or... -
Probing the structure of polymer stabilised foams
Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent... -
Effect of surfactant head group on micelle structure of drug containing micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms... -
Structure of Cellulose Nanofibril Gels
This proposal is part of a new project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils with small amounts of salt or... -
Understanding the nature of perfume / surfactant interactions at interfaces
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
Ion mediated surfactant adsorption on cellulose films
In recent work with Unilever we have been investigating the structure of gels formed by partially oxidised cellulose nanofibrils for use in sustainable personal care products.... -
How perfume structure affects surface coadsorption with anionic surfactants
In a recent EPSRC / Unilever / Oxford CASE project we have used NR to explore and develop optimised delivery mechanism for active benefit agents such as perfumes. In particular... -
Determination of the absorbed amount and location of a hydrophobic drug in su...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...
