247 datasets found

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

This proposal is part of a research programme which is focused on nano-fibres prepared by electrospinning. The programme is centered on developing an understanding of the...

Dendrimers are nanosized macromolecules with hyperbranched structures that are capable of loading all kinds of active agents for biodelivery. They are monodisperse in terms of...

We have developed a new and benign method for the production of cellulose based aerogels, highly porous materials with applications in insulation, drug delivery, gas storage,...

In the present study the acidic, anti-inflammatory drug, ibuprofen has been PEGylated using an polyoxyethylene chain of 750 molecular weight. The consequence of this PEGylation...

Short peptide sequences such as KLVFFAE form well defined beta sheet structures. Their further templating through hydrophobic interactions and hydrogen bonding is the principal...

Although microemulsions have been widely investigated as potential drug delivery vehicles, relatively little work has been performed establishing the detailed molecular...

To answer the question how DNA is packed inside the interphase nucleus at the micron scale, we propose SESANS experiment using contrast variation technique from human glioma...

In this proposal we shall explore the nature of electrospun fibres produced from blends of cellulose and polystyrene which we shall use as a model to develop high strength...

Bowel cancer is the fourth most common cancer in the UK with approximately 41,000 individuals in the UK diagnosed annually. Importantly it is estimated that over half of all...

Dynamic microdomains, resulting from lateral lipid inhomogeneity and patterning within biological membranes, have been implicated in a wide range of critical cellular processes...

Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with...

This proposal forms part of an ongoing project concerning interpenetrating network gels of starch and cellulose being developed towards applications in personal care and...

The aim of this experiment is to characterise several novel ionic liquid ¿ oil and ionic liquid ¿ water microemulsions via SANS prior to their use in the synthesis of metallic...

We hope to explore the self assembly properties of a novel chain end functionalised homopolymer to better understand its structure and enable tuning of its properties to enable...

This research project addresses an overlooked, but fundamental issue of colloid science: surfactant adsorption dynamics at nanoparticle-organosolvent interfaces. Adsorption of...

The present project aims to achieve a more detailed structural characterization by SANS of Solid Lipid Nanoparticles (SLN) and liposomes in a perspective of an inhaled anti...

The still unreached goal of nanomedicine is to deliver drugs which are only released in the diseased tissue in a controlled fashion. For this, tailorable, reproducible, and...

This proposal is the first part of a fundamental study aiming to improve understanding about technically challenging water-in-CO2 (w/c) microemulsions, by firstly investigating...

The elucidation of the compositional profile inside the polymer nanoparticles is of critical importance for applications such as water processable organic solar cells. In order...