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Non-equilibrium kinetics in highly interacting polymer mixtures
We seek to investigate the non-equilibrium phenomena of a model polymer mixture by time-solved SANS and temperature jump experiments within (a) one-phase region and (b) one to... -
Reversible folding-unfolding and structural study in protein-ionic liquid sys...
It has been recently shown that reversible thermal folding-unfolding, stabilization and high solubility of proteins (e.g. lysozyme) can be achieved when dissolved in protic... -
Controlled Assembly of Cationic Polythiophene-Surfactant Complexes
We intend to study the phase behaviour of 2 cationic polythiophenes, P3MAHT and P3ImiHT, in the presence of the perfluorinated surfactant potassium... -
Peptide resistance in asymmetric MRSA-mimetic vesicles
We have been investigating the influcence of the cationic staphylococcal lipid lysyl-phosphatidylglycerol (L-PG) on bacterial resistance to antimicrobial peptides (AMPs). Using... -
Temperature-dependent structural behaviour of the collapse transition of high...
We shall use small angle neutron scattering to investigate the structural behaviour of the temperature sensitive highly branched poly(N-isopropyl acrylamide) [PNIPAM]. These... -
Phase Separation in Organic Photovoltaic Cells
Organic photovoltaic (OPV) cells have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art solution-processed... -
The effect of anionic lipid unsaturation on the interaction with cytochrome c
While peripheral membrane protein-lipid interactions were originally considered to be solely electrostatic in nature, it is now accepted that they encompass more complicated,... -
Probing membrane localisation of molecular rotors (SANS)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Phase Behaviour of Colloidal Mixtures Under Shear
There are specific models about the influence of shear on mixtures that are distinctive from dspersions of unifom particles. Understanding the flow behaviour of mixtures of... -
Characterising micelles formed from new polymerizable amphiphiles derived fro...
Amphiphiles derived from amino acids are important functional materials. The amino, carboxyl and side chain groups present in the chemical structure of amino acids provide wide... -
Estimating carbon contents within different phases in hypereutectoid steels
Previous studies have attempted to correlate the results of metallography with neutron diffraction studies on the very high-carbon steels used in Oriental blades, and Indian... -
Hydrophobicity ¿ The Key to Polymer-Drug Conjugate Conformation
The use of polymer-drug conjugates for the delivery of drugs to specific sites of disease within the body has shown much clinical promise. It has become clear that the... -
Microemulsion Controlled Polymorph Crystallisation
Control of crystallisation is essential for many applications ranging from pharaceuticals to packaging and food preservation, yet remains extremely challenging. Recently we have... -
Structural study on the 3D arrangement of (hexa-acyl) lipid A in lipid membrane
Lipopolysaccharides are amphiphilic macromolecules indispensable for the growth and the survival of Gram-negative bacteria, one of the most diffuse classes of pathogenic... -
Opening up microemulsion phases in CO2
New types of water-in-CO2 microemulsions using mixed surfactant systems will be investigated by high-pressure SANS (HP-SANS). Exciting new results (see report on RB820030) have... -
Kinetics of the formation of eumelanin and its intermediates
The proposed research project is targeted to the investigation of the characteristics of eumelanin, a heterogeneous material insoluble in water and in any organic solvent, as... -
Structure of alkylated aza-crown ether inverse micelles
Ion transfer through fluid-fluid interfaces plays decisive roles in many natural and industrial processes. In studies of Cu(II) transport by Permeation Liquid Membrane (PLM)... -
Effect of surfactant head group on micelle structure of drug containing micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms... -
Effect of reversing lipid head group charge on vesicular properties
Zwitterionic lipids such as phosphatidylcholine (PC) are major components of the membranes that compartmentalize organisms. Although there is a large literature on PC, cationic... -
SANS experiments on phase separation in Fe-Cr based alloys
Low temperature embrittlement of stainless steels is due to phase separation and in this proposal we will further investigate the underlying mechanisms for phase separation....