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pH-Sensitive Dendrimers
Dendrimers are nanosized macromolecules with hyperbranched structures that are capable of loading all kinds of active agents for biodelivery. They are monodisperse in terms of... -
Aggregation behaviour of PEGylated ibuprofen
In the present study the acidic, anti-inflammatory drug, ibuprofen has been PEGylated using an polyoxyethylene chain of 750 molecular weight. The consequence of this PEGylation... -
Structure of oil-in-water microemulsions containing eutectic mixtures of ment...
Although microemulsions have been widely investigated as potential drug delivery vehicles, relatively little work has been performed establishing the detailed molecular... -
Cross-linked Electrospun Fibres containing Cellulose
In this proposal we shall explore the nature of electrospun fibres produced from blends of cellulose and polystyrene which we shall use as a model to develop high strength... -
Calcium and pH induced changes in silk solutions
Spider silks are known to have outstanding mechanical properties yet there is still much unknown about how the initial structure, storage and transformation of the silk proteins... -
Domain patterning in bicontinuous cubic lipid phases
Dynamic microdomains, resulting from lateral lipid inhomogeneity and patterning within biological membranes, have been implicated in a wide range of critical cellular processes... -
Silk fibrillogenesis: Morphology, structure and hydration of the intermediate...
At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of... -
Reconstitution of human dihydroorotate dehydrogenase into lipid-detergent mic...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
Formation of cellulose-starch gels: effect of cellulose source and surfactants
This proposal forms part of an ongoing project concerning interpenetrating network gels of starch and cellulose being developed towards applications in personal care and... -
Ionic liquid containing microemulsions
The aim of this experiment is to characterise several novel ionic liquid ¿ oil and ionic liquid ¿ water microemulsions via SANS prior to their use in the synthesis of metallic... -
Understanding the properties of phosphlipid-homopolymer self assembles
We hope to explore the self assembly properties of a novel chain end functionalised homopolymer to better understand its structure and enable tuning of its properties to enable... -
SANS study of lipid-based nanocarriers as inhaled drug delivery systems for a...
The present project aims to achieve a more detailed structural characterization by SANS of Solid Lipid Nanoparticles (SLN) and liposomes in a perspective of an inhaled anti... -
Conformational Evaluation of Biodegradable Model Polymer-Drug Conjugates
Previous SANS studies of anti-cancer polymer-drug conjugates (PDCs) (HPMA-Doxorubicin) identified a correlation between conjugate solution conformation and clinical results. The... -
Investigating the internal structure of two-component polymer nanoparticles f...
The elucidation of the compositional profile inside the polymer nanoparticles is of critical importance for applications such as water processable organic solar cells. In order... -
Contrast variation SANS to understand drug directed assembly of multi lamella...
Recurring infection following dental interventions such as fillings is the most common reason for failure, leading to further treatments including root canal therapy, where the... -
Mechanism of fibrous aggregate formation of caseinates as a function of proce...
This dataset has no description
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Mechanism of charging metal oxide colloids in non-polar solvents
Contrast-variation SANS (CV SANS) will be used to determine how surfactant inverse micelles interact with model metal oxide colloids. By using deuterated surfactant (D-AOT) with... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims to 1) elucidate how bile salts (BS) structure influences their interfacial behaviour and role during lipolysis; 2) to study the potential ability of... -
W/CO2 nanodispersions as an energy-saving nanoreactor separable by pressure a...
Recent studies implied an unusual headgroup (HG)-free, fluorocarbon (FC) surfactant Nohead FC6-HC4 to form stable, W/CO2 nanodispersions (W/C NDs). With the unusual surfactant... -
Polymer layer structure in stabilised metal nanoparticles for heterogenous ca...
The controlled synthesis of precious metal nanoparticles of the appriopriate chemical composition, optimised size and morphology for use in catalysis is an ongoing experimental...
