End-Game: Cornering Solvent Effects on H-Addition in Green Tea Anti-Oxidants

DOI

Our ongoing project to characterise radical scavenging by the green tea anti-oxidant EGCG and its D-ring analogue, (3,4,5-(OH)3-Bz) is near-complete. ALC-MuSR experiments on the powder samples were successful for both the EGCG and the analogue. However, we had to answer the question of the influence of solvent to make these exciting results biologically-relevant and a highly-impacting publication. Experiments on 3,4,5-(OH)3-Bz in EtOH and H2O generated sufficient statistics to confirm H-addition occurring in both solvents. Unfortunately, the experiment for EGCG in EtOH failed to produce spectra with good resolution due to time-limitations caused by low solubility of EGCG in EtOH (12 mM). To complete the project we require further statistics for EGCG in EtOH, and (at least) have a qualitative idea of its behaviour in H2O; 'biased scans' in selected field regions facilitating the latter.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24088373
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24088373
Provenance
Creator Dr Iain McKenzie; Dr Gregory Chasse; Ms Sara Abbas; Mr Fouad Husseini; Miss Nada Kurdi
Publisher ISIS Neutron and Muon Source
Publication Year 2015
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2011-12-09T13:39:45Z
Temporal Coverage End 2012-03-08T08:48:31Z