Internally supported liposomes (ISLs) are composed of polymeric spheres enclosed by liposomes. Although very little research has been done on ISLs, understanding their properties could have important implications for many areas of scientific endeavour. Here, we propose using SANS to study the structure and behaviour of ISLs, including details such as how closely the liposome enfolds the core particle and the effect of the internal support on the lipid phase behaviour. The study is also supported by preliminary results from dynamic light scattering and electron microscopy. Overall, it is expected that the work will reveal important insights into the relationship between ISL structure and stability and that this in turn will lead to a better understanding of liposome biophysics as well as possible avenues for developing new functional materials.