31 datasets found

Although microemulsions have been widely investigated as potential drug delivery vehicles, relatively little work has been performed establishing the detailed molecular...

Poly- and perfluoroalkyl substances (PFASs) have been used in various industrial applications and consumer products, but have received increasing global concern due to their...

Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using...

Structure and functions of cell membrane are susceptible to alterations as a consequence of interactions with chemical species. The objective of the proposed experiment is to...

In recent years we have had considerable success with the surface modification of amorphous and crystalline thermal plastic polymers using multi-end functional additives. In...

Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the...

Plastic bags are used as containers for storage of donated blood. These bags are typically made out of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into...

N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered...

Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by...

Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a...

Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus...

A cell membrane can contain hundreds of different lipid molecules, but our understanding of the dynamics of cell membranes is very limited. As a result of a collaboration...

We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This...

We propose to investigate the role of lateral phase separation on LPS insertion into model membranes and the effects of target membrane structure and composition. A comparison...

The proteins of the outer membrane of Gram-negative bacteria are critical for bacterialsurvival, from providing basic physiological functions, to aiding virulence and...

Asymmetry across biological membranes is vital for a wide range of organelle and cellular functions. Significant differences in lipid composition have been found between the...

The 1,2- dichloroethane (DCE)/water interface is important because of its suitability as an electrochemical interface between two immiscible electrolyte soloutions. An issue of...

Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment....

Ethanol plays an important role in the human metabolism. It is in particular known to act as a drug enhancer by increasing trans-membrane permeability, and as an anesthetic....

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