132 datasets found

This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an...

Abstract: Apatites (general formula Ca5(PO4)3(OH,F,Cl)) are suitable materials for nuclear waste remediation and storage because they can incorporate actinides in their...

At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of...

MISANS is the combination of Modulation of Intensity Emerging from Zero Effort (MIEZE) and Small Angle Neutron Scattering (SANS). SANS is used to determine the microscopic...

Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection....

GluR0 is a glutamate sensitive potassium ion channel from the cyanobacterium Synechocystis which has been identified via primary structural sequencing to be similar to...

Combining structural information about silk proteins in solution whilst undergoing mechanical shear will open a new window into silk production in vivo and provide valuable...

Measurements are required for Sans2d resolution checks and also the overlap of the two Sans2d detectors. Proposal submitted to panel and they deemed it should be done as...

Nanogranular thin films of FexAg100-x (x=7,15,35) are an excellent system to study the interplay between the nanostructure and the magnetic behaviour, which is triggered by the...

Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their...

There is exciting potential for SANS to resolve an important problem in homogeneous catalyst chemistry. The Pd-chiral catalyst 1+ below has significant pan-industrial potential...

Although microemulsions have been investigated as potential drug delivery vehicles, little work has been performed establishing the detailed molecular architecture of the...

Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they...

Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...

We propose to use SANS to probe the self organised formation of P3HT nanowires in a solution of deuterated chlorobenzene over a 48 hr period in order to better understand the...

Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds...

Phase behaviour studies have identified hydrogen bonding as a key aspect in polymer solubility in fluorinated liquids, both in terms of solute-solvent and solute-solute...

NDA Agreement No. 1011-169 Lubrizol No. 36695

This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing...

Cytochromes P450 play a key role in drug metabolism in man. Electrons are supplied to the cytochromes by NADPH through the flavoprotein NADPH-cytochrome P450 reductase (CPR)....