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The effect of polymer therapeutics on the structure of mucin solutions toward...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Self assembly of thermoresponsive gels
Thermoresponsive gels are widely used for tissue engineering and drug delivery applications. They consist of a thermoresponsive polymer that self-assembles in a 3D network when... -
Investigation on the structural properties of doxorubicin-loaded PEGylated li...
Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the... -
Control of oil exchange dynamics in microemulsions by amphiphilic copolymers
A very important property of O/W microemulsions is the exchange dynamics of the oil molecules. So far little is know about that, despite the fact that its control is crucial for... -
Silk fibrillogenesis: Morphology, structure and hydration of the intermediate...
At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of... -
Structural studies of Staufen1 in complex with Upf1, a crucial assembly in ge...
Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated... -
Formation of cellulose-starch gels: effect of cellulose source and surfactants
This proposal forms part of an ongoing project concerning interpenetrating network gels of starch and cellulose being developed towards applications in personal care and... -
Understanding the properties of phosphlipid-homopolymer self assembles
We hope to explore the self assembly properties of a novel chain end functionalised homopolymer to better understand its structure and enable tuning of its properties to enable... -
Rapid microfluidic phase mapping of SDS:water:butanol
Sodium dodecyl sulfate (SDS) is an anionic surfactant, extensively employed in cosmetics and personal care, as well as in pharmaceuticals and food products. Surfactants are... -
Conformations in partially mixed block copolymers of partially deuterated pol...
Nascent 'disentangled' block copolymers of Ultra-high Molecular Weight Polyethylene (UHMWPE) with a reduced number of entanglements were synthesized having protonated (hPE) and... -
Constructing analogues of Gemini and oligomeric surfactants using polyamines
Gemini or oligomeric surfactants, where two or more alkyl chains and headgroups are connected via spacer groups, have interesting and potentially important properties which make... -
Rheo-SANS on calcium caseinate under shear and heat
Producing meat analogue instead of real meat is one effective way to reduce carbon emission and improve animal welfare. Calcium caseinate is a prominent candidate for making a... -
Structural characterisation of a transmembrane biological electron conduit us...
Many bacteria are able to respire using solid minerals and metals as electron acceptors in the absence of oxygen or other diffusible substrates. In Shewanella oneidensis this... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims to 1) elucidate how bile salts (BS) structure influences their interfacial behaviour and role during lipolysis; 2) to study the potential ability of... -
SANS from photoconductive hydrogel mixtures and their gelators.
Hydrogels are formed from a self?assembled network of fibres made up of small molecules (gelators) trap and hold water at just 1% by weight, or less, from the solution they are... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Investigating the structure of modular ionogels for catalysis, biocatalysis, ...
Ionogels are a new class of soft matter that have only really become subject of detailed research in the past decade. As a result, much of the contemporary literature is still... -
Zwitterionic Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Structure and gelation in PVDF-based polymer systems for Li-ion battery appli...
Lithium ion batteries are the power source of choice for portable electrical devices owing to performance in terms of high specific capacity and reliability. Liquid electrolyte... -
Probing the structure of hybrid polymer-silica nanoparticles
Organosilica nanomaterials have received substantial attention in the past two decades with a number of reports describing their synthesis, structural features, properties and...