-
The effect of polymer therapeutics on the structure of mucin solutions toward...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Self assembly of thermoresponsive gels
Thermoresponsive gels are widely used for tissue engineering and drug delivery applications. They consist of a thermoresponsive polymer that self-assembles in a 3D network when... -
Structure determination of gelled cellulose nanowhisker assemblies
We have developed a new and benign method for the production of cellulose based aerogels, highly porous materials with applications in insulation, drug delivery, gas storage,... -
Shaping silica to mesoscale architectures at room-temperature
Hierarchical zeolites with molecular order at both the micropore (<2nm) and mesopore (2-50nm) level are able to combine confinement effects in catalysis without suffering... -
Investigation on the structural properties of doxorubicin-loaded PEGylated li...
Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the... -
Cubosomes as biosensors: A kinetic study of changes to lattice parameter and ...
Lipid bicontinuous cubic phases are self-assembled three dimensional lattices, consisting of a single periodic bilayer interwoven by two independent water channels. They can be... -
Packing of DNA in glioma nuclei
To answer the question how DNA is packed inside the interphase nucleus at the micron scale, we propose SESANS experiment using contrast variation technique from human glioma... -
CO2-philic Low Surface Energy Surfactants for applications in Enhanced Oil Re...
In recent years, there has been an enormous interest in the study of surfactants for supercritical CO2 (scCO2). One important potential application of these materials is in... -
The Effect of Polydispersity on the Self Assembly of Diblock Copolymers
Block copolymers are of interest due to their ability to undergo microphase separation. Originally block copolymers were produced with a low polydispersity index (PDI) as they... -
Structural studies of Staufen1 in complex with Upf1, a crucial assembly in ge...
Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated... -
Formation of cellulose-starch gels: effect of cellulose source and surfactants
This proposal forms part of an ongoing project concerning interpenetrating network gels of starch and cellulose being developed towards applications in personal care and... -
Understanding the properties of phosphlipid-homopolymer self assembles
We hope to explore the self assembly properties of a novel chain end functionalised homopolymer to better understand its structure and enable tuning of its properties to enable... -
Gelation of oxidised cellulose nanofibrils with industrially relevant anionic...
This proposal aims to investigate the interaction of oxidised cellulose nanofibrils (OCNF) and anionic surfactants, such as sodium laureth sulphate (SLES) and sodium lauroyl... -
Magnetic alignment of fullerene-containing gel fibers
The magnetic field-driven alignment of a photoconductive gel formed by an alkylated fullerene-C60 in n-alkanes will be studied. These could find application in next-generation... -
SANS study of synthesis of interpenetrating polymer networks in supercritical...
We use SANS to study synthesis of interpenetrating polymer network in supercritical CO2 in situ at sans2D. The initial system contains an inorganic polymer network, hydrophilic... -
Conformational Evaluation of Biodegradable Model Polymer-Drug Conjugates
Previous SANS studies of anti-cancer polymer-drug conjugates (PDCs) (HPMA-Doxorubicin) identified a correlation between conjugate solution conformation and clinical results. The... -
Conformations in partially mixed block copolymers of partially deuterated pol...
Nascent 'disentangled' block copolymers of Ultra-high Molecular Weight Polyethylene (UHMWPE) with a reduced number of entanglements were synthesized having protonated (hPE) and... -
Understanding the network change in reversible photochromic hydrogels
Photochromic devices are ones which change colour upon the irradiation of light. These devices can be used a sensors, logic gates and privacy windows etc. Here we show and... -
Detailed structures of surfactant micelles
Measurements are required for Sans2d resolution checks and also the overlap of the two Sans2d detectors. Proposal submitted to panel and they deemed it should be done as... -
Constructing analogues of Gemini and oligomeric surfactants using polyamines
Gemini or oligomeric surfactants, where two or more alkyl chains and headgroups are connected via spacer groups, have interesting and potentially important properties which make...
