19 datasets found

Internally supported liposomes (ISLs) are composed of polymeric spheres enclosed by liposomes. Although very little research has been done on ISLs, understanding their...

Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation or crosslinking resulting in lack of...

Gradient and block copoly(2-oxazoline)s have been prepared comprising a partially deuterated hydrophilic poly(2-methyl-2-oxazoline) part and a hydrogenated...

The very heterogeneous, but non-random, arrangement of lipids and proteins in cell membranes are of major scientific interest and led Simons and Ikonen to propose that ¿rafts,¿...

Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their...

This proposal aims to explore these dispersed lamellar phases with a variety of F7H4 derivatives,to help understand their formation in supercritical CO2 (sc-CO2). The focus is...

Bacterial endotoxins, or lipopolysaccharide (LPS), released from the gram negative bacterial membrane, form different aggregates in solution which morphology depends on the type...

Increased environmental pressures and awareness is promoting a major drive towards an increased use of biosurfactants to produce more biosustainable and biodegradable consumer...

The objective is to refine current understanding about the mechanism of hydrotropy with respect to polarity and electrostatic character of hydrotropes and hydrophobic solutes...

Associative polymers have a very important role as rheological modifiers, due to their ability to form interconnected networks of hydrophobic domains. Additionally,...

In recent years much progress has been made in the design of surfactants that are soluble in liquid CO2; hence these additives able to modify physicochemical properties...

Asymmetry across biological membranes is vital for a wide range of organelle and cellular functions. Significant differences in lipid composition have been found between the...

In a one-pot synthesis, we are able to produce spherical gold nanoparticles capped with antibiotics, without the use of other chemicals by using the antibiotic as the reducing...

Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR...

We propose a SANS experiment to investigate a structural transition involving an alkylated fullerene-C60 (an alkyl-aromatic hydrophobic amphiphile) in alkane solvents from an...

We will study the kinetics of the early stages of aggregate formation in protein solutions under conditions that are known to result in the formation of amyloid protein fibres...

This collaborative study with the chemical engineering groups from University of Innsbruck, Austria and Aristotle University of Thessaloniki, Greece is part of this large EU...

Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...

This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an...