Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and manipulate surfactant adsorption at the air-water interface and to promote surface multilayer formation. The measurements will explore a wider range of biogenic amine structures and build upon the significant insights obtained for the biogenic amines, putrescene, spermidine, and spermine, recently studied. The work is supported by a Leverhulme Trust Grant, (EM-2013-017, and has potential for widespread applications and in a greater understanding their biological role.