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Structure of lipid monolayers following oxidative damage
Lipids form the major component of cell membranes, which separate the contents of the cell from the external environment. The oxidation of lipids within biological membranes is... -
Influence of Alkyl Chain Fluidity on the Membrane Binding Activity of Cationi...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improves patient compliance and can provide a release for long... -
Towards optimised detergency at low temperatures
This proposal is about the development of sustainable detergency based formulations, based on the blending of biosurfactants with conventional surfactants, and is part of a CASE... -
The origins of Biosurfactant self assembly
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
The role of biogenic amines in lipopeptide biofilm formation
Pore forming lipopeptides, such as Tolaasin, are produced by pathogenic mushroom bacteria, and are implicated in diseases such as ¿brown blotch¿ disease. They have potential... -
Adsorption of modified polysorbate (Tween) surfactants at the air-water inter...
The nonionic polysorbate (Tween) surfactants are an important class of food grade surfactants. They are extensively use in emulsion and foam stabilisation, and are increasingly... -
Manipulating surface multilayer structures in hydrophobin-Tween mixtures
Increased environmental pressures and awareness is promoting a major drive towards an increased use of biosurfactants to produce more biosustainable and biodegradable consumer... -
Lipid bilayers suspended beneath the air/water interface for neutron reflecti...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,... -
Interactions of native vs. modified protamines with Gram-negative model biome...
Protamines are cationic antimicrobial peptides found commonly in the sperm cells of fish such as herring and salmon that are particularly active against food-borne Gram-negative... -
Changes to the structure of natural lung surfactant following OH(aq) radical ...
The presence of lung surfactant at the air-water interface of the lung is vital to prevent alveolar collapse. Exposure to environmental pollutants can cause the formation of... -
The interpenetration of two poly(ethylene oxide) polymer brushes under confin...
Coating two surfaces with polymer brushes has been shown on many occasions to reduce friction by orders of magnitude. These ultra-low frictions are believed to stem from be the... -
Elucidating the effect of BTHC on DMPC monolayers
Plastic bags are used as containers for storage of donated blood. These bags are often made of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into the blood... -
Night-time oxidation of meat-cooking emissions: kinetics and products of mixe...
We propose to study the two unsaturated surfactant palmitoleic acid (POA) and oleic acid (OA) and three binary mixtures (1:1) stearic acid (SA)/OA, SA/POA and OA/POA exposed to... -
Spontaneous surface multilayer formation in oligoamine ¿ surfactant mixtures
This proposal is part of a major EPSRC (EP/GR065705)/Unilever funded programme to develop and control the spontaneous formation of surfactant multilayer structures at... -
Interfacial conformation of antibody and antigen binding capacity
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Understanding the insertion of antibiotic toxins into the gram negative outer...
The gram-negative bacterial membrane is of extreme medical importance. Two of its major components are lipopolysaccharides (LPS's) and integral membrane proteins. Porins are... -
Biosurfactant conventional surfactant mixing. Where nature does it better ?
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Kinetics of surfactant multilayer formation / dissolution at interfaces
The formation of multilayer structures at surfaces and interfaces from self-assembly in mixed surfactant and in polymer / surfactant mixtures has been recently reported, and... -
Competetive adsorption in hydrophobin / protein mixtures at the air-solution ...
Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self assemble at interfaces and in solution. This... -
Surfactant adsorption onto model surfaces
In the context of home and personal care products, studying surfactant and mixed surfactant adsorption ion model solid surfaces, which mimic real surfaces such as fabrics, hair...