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Surface activity of antibacterial agents
This proposal is aimed at understanding the surface activity of the antibacterial agent, Triclosan, in the presence of surfactants. We request NR beam time on SURF to... -
Morphology and Phase Diagram of Thermoresponsive Polymer-Protein Conjugates
Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with... -
Spontaneous surfactant multilayer formation at interfaces induced by multival...
The spontaneous formation of multilayer structures at interfaces from surfactant self-assembly is now emerging as an important structural signature associated with a wide range... -
Interfacial layer structure of designed lipopeptides at the solid/water inter...
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Neutron reflectivity of water soluble conjugated polymer/surfactant films
Water-soluble conjugated polymers (WSCP) are an important class of materials which have received great attention as active materials in optoelectronic devices and in biosensing.... -
Evolution of complex surface structures in LAS / nonionic surfactant mixtures
This proposal is part of a broad programme of collaborative research between RAL / Oxford and Unilever, using predominantly scattering techniques to investigate the nature of... -
Adsorption of modified PEI / SDS mixtures at the solid-solution interface
Polymer-surfactant mixtures are extensively used in a wide range of domestic, industrial and technological applications. This proposal is part of a collaboration between Oxford... -
NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Solution Aggregation of Short Peptide Amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading interfacial adsorption and solution nano-aggregation.... -
Interfacial layer structure of lipopeptides adsorbed at the air/water interface
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Interaction of polypeptide with surfactant on the surface of water
This proposal constitutes part of our ongoing study towards understanding the adsorption of collagen based polypeptide and its interaction with ionic surfactants at the... -
Copy of: The origins of Biosurfactant self synergy
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Steroidal drug containing dodecyl sulphate monolayers: effect of counterion
An number of potential drugs, including steroidal drugs are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant... -
Impact of Elasticity on Surface Wetting
We have recently characterised a surface wetting transition for a low molecular weight oligomer in a high molecular weight rubbery polymer. Although weak surface segregation of... -
Surfactant Segregation in Plasticised PVA
PVA film is widely used as a non-toxic water soluble polymer. This proposal relates to its use in unit dose detergent pouches where plasticised PVA film stores a concentrated... -
Polymer conjugates for drug delivery
Complex polymer architectures such as comb polymers have been studied for their highly customisable chemical properties. Potential applications have been identified in a wide... -
The effect of bilayer rigidity on the interactions with perfluoroalkyl compounds
Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment.... -
Interactions between a mixture containing two cationic polyelectrolytes and a...
Recently there has been a vast expansion in understanding about the interactions between oppositely charged polyelectrolyte/surfactant mixtures. The use of neutron reflectometry... -
Surface properties of biogenic polyaminesurfactant mixtures
Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and... -
How polymer functionality influences multilayer formation at the interface in...
Spontaneous multilayer formation at interfaces from surfactant self assembly is emerging as an important structural signature associated with a wide range of potential...