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Interfacial adsorption of monoclonal antibodies and antigen binding
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Formulating polymer solutions to stabilise polymeric foams
Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent... -
The action of membrane lytic compounds on model membranes.
The study of antifungal and antibacterial action is of great interest and there are still many unknowns concerning the action of membrane lytic materials, and the way that... -
Structure determination of solution aggregation of single alkyl chain PC surf...
We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of... -
Biosurfactant conventional surfactant mixing. Where nature does it better ?
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Kinetics of surfactant multilayer formation / dissolution at interfaces
The formation of multilayer structures at surfaces and interfaces from self-assembly in mixed surfactant and in polymer / surfactant mixtures has been recently reported, and... -
Structural insight into the mechanistic process of permeabilization into mode...
The aim of this study is to try to understand how antimicrobial peptides bind to model lipid monolayers mimicking different cell membrane types. Following our previous work,... -
Multilayering of Methyl Ester Sulphonates at the Air-Aqueous Interface: Effec...
Surfactants usually form a single layer of molecules at the surface of water. We have shown that under certain conditions more than one layer may form. When this happens the... -
Probing perfume surface delivery / retention rates in-situ
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
Competitive adsorption in hydrophobin / protein mixtures at the solid-solutio...
Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self-assemble at interfaces and in solution. This... -
Interaction between Rubisco and SDOBS at an air-water interface
Protein-surfactant interactions at an interface play an important role for broad applications in the chemical, dairy, cosmetic and pharmaceutical industries. Rubisco is the most... -
Interfacial layer structure of designed linear lipopeptides
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Neutron Reflection Studies on Adsorption of Myristoyl-L-Carnitine at the Air/...
The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to... -
The structure of glycerol mono oleate at the iron oxide/dodecane interface
The reliability of combustion engines is enhanced by lubrication, which provides wear protection along with reduced emissions and fuel consumption through the minimisation of... -
Surface properties of biogenic polyamine-surfactant mixtures
Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and... -
Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Interaction of Surfactant with Model Lipid Membranes: Influence of Surfactant...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long... -
Phase behaviour in Polymer-Photovoltaic Thin Film Blends
In polymer-fullerene based photovoltaic systems the phase behaviour of the blends is poorly understood and remains a fundamental stumbling block to improvements in device... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
A sustainability study of the galvanic deposition of silver from novel deep e...
The immersion deposition of silver onto copper and brass from deep eutectic solvents (DES) is a novel method for protecting the surface of printed circuit boards. Background...