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The mechanism of lipid transport in Gram-negative bacteria
The bacterial cell envelope is one of the best targets in antimicrobial development. This proposal focuses on understanding how lipids move between the membranes of the... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Neutron Reflectivity Study of Protein Adsorption onto Cell Membrane-inspired ...
We grafted 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer brush from the silicon wafer surface through Cu (0) mediated controlled radical polymerization (CuCRP) to mimic... -
Surfactant mixing at hydrophilic solid/liquid interfaces: (A) air/water measu...
The overall objective is to model the amount and composition of adsorbed mixtures of three types of zwitterionic surfactant and two charged surfactants at the silica/water... -
Phospholipid exchange between tethered bilayers and vesicles
Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by... -
The Interaction of wild-type and mutant Puroindoline B with Model Bacterial M...
Bacterial and fungal infections of cereal crops pose a considerable risk to global food security. Typically plant pathogens are controlled through the use of chemical agents... -
NR Study of Selective Binding of a-Helix Antimicrobial Peptides onto Bacteria...
In this work we will explore how to use PolRef to study the binding of our rationally designed peptide amphiphiles onto floating lipid bilayers mimicking G- bacterial and red... -
The Interactions of Blood Components with Models of the Gram Negative Bacteri...
One of the major challenges in the fight against antimicrobial resistance is the development of antimicrobial compounds that selectively disrupt bacterial membranes and leave... -
Charged nanogels and their ability to penetrate model lipid membranes
Drug delivery through the skin is an important route for administration of therapeutic agents. However, the outermost layer of the skin, the stratum corneum provides a... -
Comparative Interaction Studies of Antimicrobial Agents on Floating Asymmetri...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
A model system to study the important interactions of proteins from extreme e...
Organisms which live in the presence of large quantities of salt are known as halophilic (meaningsalt-loving). Halophilic proteins are of great interest due to their ability to... -
INTERACTIONS OF PAMAM DENDRIMERS WITH DESIGNER BIOSURFACTANTS AT THE SOLID/LI...
Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),... -
Interaction of polypeptides with surfactants: aqueous solution aggregation
This proposal constitutes part of our ongoing study towards understanding how collagen based polypeptides interact with ionic surfactants using SANS. Both SDS and C12TAB will be... -
Magnetic Proximity Effects in Ferromagnetic-Superconducting Spin Valves
The recent experimental verification of the unique odd-frequency spin triplet superconductivity in artificial thin film ferromagnetic-superconducting structures is likely to... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Adsorption of NHE1 intracellular domain on lipid bilayers
Recently the intracellular domain (ICD ) of the Na+/H+ exchanger isoform 1 (NHE1), is a transmembrane protein, has been identified as an intrinsically disordered protein.... -
Effect of structure on the location of hydrophobic drugs in ionic surfactant ...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of... -
Interfacial conformation of antibody and antigen binding capacity
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
The Interaction of Small Cationic Amphiphillic Antimicrobial Proteins with Fr...
Protein-membranes interactions are fundamentally important to biological function. We have developed advanced models of the Gram negative bacterial outer membrane and have... -
Temperature-induced structural changes of Organic Friction Modifier films at ...
Engine oils provide lubrication to moving components in engines, improving vehicle lifespans whilst reducing emissions and fuel consumption by minimising friction. A common...
