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Chain exchange mechanism of complex coacervate core micelles
Complex coacervates have been studied for a long time for their medical applications and unusual physical-chemical properties: they are dense networks of poly-electrolytes, that... -
SANS Investigation on Packing Structure of Proteasome Activator 28
Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large... -
Selective adsorption of polymer on Janus particles
Janus particles, bearing two distinct compositions on the surface of the same particle, have attracted much attention recently as a way to finely tune morphology and... -
SANS study of effect of water soluble polymers on aggregation behaviour of co...
Aggregates of the cationic conjugated polyelectrolyte (CPE) HTMA-PFP with poly(vinyl alcohol) (PVA) will be studied in aqueous solutions using SANS. Previous fluorescence,... -
SANS Contrast Matching Studies of Radiation-grafted Anion-exchange Membranes
We request two days beam time on SANS2D for the study of radiation-grafted anion-exchange membranes, both dry and hydrated under different ratios of D2O/H2O. These materials... -
Interaction of polypeptide with surfactant: SANS study of solution aggregation
This proposal constitutes part of our ongoing study towards understanding the solution aggregation of collagen based polypeptides and their interactions with model surfactants.... -
Controlling diblock co-polymer morphologies via selective solvent annealing -...
Diblock co-polymers consist of two polymer chains with different chemical properties tied together at a central linking block. The interactions between the two blocks result in... -
Binary colloidal mixtures - SANS contrast variation to study high concentrati...
Mixtures of colloidal particles of essentially two different sizes are commonly used in technological applications such as film formation on surfaces, paper coatings, etc.... -
Influence of polymer molecular weight on polymer stabilized lipid nanodiscs
Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Poly(Styrene-Maleic Acid) stabilized lipid nanodiscs have a... -
Encapsulation of monomers in cationic surfactant-polymer solutions
We have been studying the solution interactions leading to formation of solid polymer-surfactant films at the air-solution interface. We wish to use the mesostructures in the... -
DNA unwinding mechanism of the archaeal helicase PabMCM
The process of cell division requires precise duplication of the genetic material. The separation of the two strands of DNA and the progression of the replisome are driven by... -
Hydrophobicity ¿ The Key to Polymer-Drug Conjugate Conformation
The use of polymer-drug conjugates for the delivery of drugs to specific sites of disease within the body has shown much clinical promise. It has become clear that the... -
TK49_TRANS
This dataset has no description
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Encapsulation of Non-Steroidal Anti-Inflammatory Drugs Using Novel Pluronic G...
The research topic is encapsulation of a hydrophobic drug, flurbiprofen, using novel amphiphilic graft copolymers (AGCs). The AGCs of interest are shown in Figure 1: Preliminary... -
Solubilisation in Zwitterionic Micelles: Effect of Structure
The project aims to probe the relationship between surfactant structure, the micelles formed in solution, and the type of drug molecules that the micelles solubilise. Once... -
Small angle neutron scattering experiment of a novel pH and temperature sensi...
The aim of the present study is to investigate the effect of different stimuli on a novel iron oxide core shell nanoparticles. The system is composed of a magnetite core with a... -
Dynamic ferromagnetic domains in a frustrated 1-d chain system
We propose to carry out a small angle scattering experiment on LOQ or SANS2D on a frustrated Ising chain system. SrHoCrO6 is based on ferromagnetic chains arranged on a... -
Structure and interactions in model and real anti-reflective coatings
This proposal seeks to exploit contrast variation SANS to study a multi-component system, spanning a wide range of colloidal length scales. The multi-component system under... -
Organogels for applications in CO2
This proposal aims to explore organogel systems, like those recently decsribed1-3, but made from new CO2 philic surfactant-gelators. These have been synthesised to feature... -
Metal ion induced condensation of anionic fluorine-based conjugated polyelect...
In the proposed experiments we aim to characterise the structures of aggregate species formed when divalent metal ions, such as calcium(II), interact with the anionic conjugated...
