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Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an... -
Investigation of the structure and formation of alphasynuclein-lipid co-aggre...
Alpha-synuclein is tan intrinsically disordered protein whose aggregates are an hallmark of Parkinson's Disease (PD). Alpha-syn is known to associate with lipid membranes and... -
Function and Structure of Reconstituted Neurotransmitters in biomembranes
Neurotransmitter transporters recognize biogenic amines dopamine, serotonin, noradrenalin and γ-amino butyric acid (GABA). They all belong to the family of... -
GISANS directed to study lipid bilayer structures on nanowire arrays
Nanowires are increasingly being used in life science to interact with living cells, for example as nanometer probes. The interaction between the cell membrane, i.e. a lipid... -
Structural study on the 3D arrangement of (hexa-acyl) lipid A in lipid membrane
This study will focus on the structural investigations of the bilayers formed on silicon substrates in which the outer leaf consists of DOPE/LPS mixtures. We aim is to achieve... -
Dynamics of Protein-Confined Water in Polymer Vesicles: A Feasibility Study
When we confine water in extremely small spaces it starts to move extremely slowly. This behaviour is critical to helping biological molecules like proteins function normally.... -
Kinetics of protein and protein mixture adsorption at the air/water interface
Many proteins exhibit a lag in lowering the surface tension at the air-water interface. The origin of this lag is not well understood either experimentally or theoretically. The... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
INS investigation of the effects of hydration on the dynamics of natural silk...
Silk materials have been the focus of renewed attention because they exhibit extraordinary mechanical strength and toughness.Two main factors are critical for understanding... -
Modes of protein adsorption at polyethylene oxide brushes of various polymer ...
We wish to understand the mechanism to which polymer brushes such as PEO resist the adsorption of protein and thus offer biocompatibility for various surface applications.... -
b-crystallin 25C 002
This dataset has no description
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SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Structural development in Whey protein polymer composite solutions for electr...
This is part of an on-going investigation into nano/micro scale sized polymer fibres at the University of Reading, prepared through the process of electrospinning. Currently we... -
Structural studies of protein at the oil-water interface
We would like to measure the adsorption isotherm for protein, milk B-casein using neutron reflectometery at the oil-water interface. These measurements will be carried out for... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Transition and signature of protein domain motion in Phosphoglyceratekinase (...
In a series of neutron spin-echo experiments (NSE) on the proteins alcohol dehydrogenase (ADH) and phosphoglycerate kinase (PGK) large scale large amplitude domain motions with... -
Structural characterization of a series of polymer-protein conjugates for chr...
Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for... -
Probing the Kinetics of Assembly and Triggered Dispersion of Peptide-Function...
Peptide-functionalized nanoparticle (NP) aggregates have significant potential as biosensors (for specific enzymes) due to their high sensitivity, modular design and simple...
