INS investigation of the effects of hydration on the dynamics of natural silk worm protein

DOI

Silk materials have been the focus of renewed attention because they exhibit extraordinary mechanical strength and toughness.Two main factors are critical for understanding silks: the nanoscale semi crystalline folding structure, which gives high strength and exceptional toughness and the degree of hydration, which acts to modify these properties. Understanding and controlling these factors are the key to the functionality of protein elastomers. Silk fibroin is an ideal choice for (bio)material design-study and to probe H2O effects on protein dynamics, its interaction with and role in denaturation of proteins. The key molecular interactions are hydrogen bonds, one of the weakest chemical bonds known. Using a novel method to adjust the H2O content in situ with unprecedented accuracy and precision we aim to investigate effects of hydration on the protein torsional and vibrational dynamics.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24090583
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24090583
Provenance
Creator Dr Tilo Seydel; Dr John Larese; Mr Andy Hicks; Mr Nathaniel Bass; Mr Christopher Crain; Dr Luke Daemen; Dr Thomas Arnold; Dr Sourav Adak; Mr Nicholas Strange
Publisher ISIS Neutron and Muon Source
Publication Year 2016
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2013-06-06T08:10:56Z
Temporal Coverage End 2013-07-23T07:37:16Z