29 datasets found

This proposal continues our research on mesostructured surfactant templated polymer films that form spontaneously at the air-water interface. Our recent research has shown it is...

Coating two surfaces with polymer brushes has been shown on many occasions to reduce friction by orders of magnitude. These ultra-low frictions are believed to stem from be the...

The gram-negative bacterial membrane is of extreme medical importance. Two of its major components are lipopolysaccharides (LPS's) and integral membrane proteins. Porins are...

Dendrimers are a unique class of nano-structured vehicles for drug and gene delivery into intracellular targets. Their surface chemistry influences their transport across...

Nanodiscs are self assembled complexes of phospholipids and a class of amphipathic helical proteins termed membrane scaffold proteins . The proteins and lipids self-assemble...

In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied...

As part of a wider study we are studying the effects of polymer architecture between cyclic and linear polymers. From ATR-FTIR measurements we observe clear differences between...

DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We...

DNA is an extremely versatile building material for the development and assembly of functional nanostructures and nanodevices. There are numerous examples of DNA based...

Studies of internal dynamics in the pico seconds timescale, of cyt c trapped in MCM-41, would allow the forms, geometry, amplitudes and time-dependence of the motions involved...

We will use time-resolved specular neutron reflectivity measurements to follow the in-situ growth of polymer brushes by surface-initiated ATRP. This will enable us to determine...

As part of a wider study we are investigating the effects of polymer architecture between cyclic and linear polymers. From ATR-FTIR measurements we observe clear differences...

For polymer vesicles to act as effective molecular delivery systems we must efficiently encapsulate a molecular payload within the vesicle. We would like to use neutron...

Surfactant-silica self-assembly processes have been extensively studied since the discovery of M41S mesoporous materials in 1992. Mesoporous silicate films can be grown from...

Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the...

The key to the use of polymer vesicles as effective molecular delivery systems is in the ability to efficiently encapsulate a molecular payload within the vesicle. We would like...

Of concern to the bioprocessing industry is the manner in which polysorbates included in solution formulations of antibodies affect the kinetics and equilibrium state of...

This proposal continues our research on mesostructured surfactant templated polymer films. The films are robust and form spontaneously at the air-water interface. Recent...

Significant research has been given towards synthesis and characterisation of electrolyte materials with high proton conductivity for intermediate temperature range (200-600°C)...

Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),...