29 datasets found

Polymeric films thinner than a 100 nm exhibits a variation of the glass transition temperature of a few tens of degrees and can brake up into discrete islands when heated near...

We have previously observed formation of polymer-surfactant films at the air-water interface having a range of structures including 2D hexagonal, bicontinuous cubic and lamellar...

This proposal continues our work into surfactant templated films formed from surfactant/polyelectrolyte solutions. Recently we have been studying the encapsulation of...

In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied...

Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the...

The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿...

This is one of a pair of linked proposals, one for SURF and one for INTER. The voltage response of poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) weak polybase brushes...

The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will...

In a recent experiment carried out on SURF we have shown that on addition of ethanol to a DPPC model membrane, the anaesthetic initially diffuses to the bilayer surface followed...

Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),...

Significant research has been given towards synthesis and characterisation of electrolyte materials with high proton conductivity for intermediate temperature range (200-600°C)...

This proposal continues our research on mesostructured surfactant templated polymer films. The films are robust and form spontaneously at the air-water interface. Recent...

Of concern to the bioprocessing industry is the manner in which polysorbates included in solution formulations of antibodies affect the kinetics and equilibrium state of...

The key to the use of polymer vesicles as effective molecular delivery systems is in the ability to efficiently encapsulate a molecular payload within the vesicle. We would like...

Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the...

Surfactant-silica self-assembly processes have been extensively studied since the discovery of M41S mesoporous materials in 1992. Mesoporous silicate films can be grown from...

For polymer vesicles to act as effective molecular delivery systems we must efficiently encapsulate a molecular payload within the vesicle. We would like to use neutron...

As part of a wider study we are investigating the effects of polymer architecture between cyclic and linear polymers. From ATR-FTIR measurements we observe clear differences...

We will use time-resolved specular neutron reflectivity measurements to follow the in-situ growth of polymer brushes by surface-initiated ATRP. This will enable us to determine...

Studies of internal dynamics in the pico seconds timescale, of cyt c trapped in MCM-41, would allow the forms, geometry, amplitudes and time-dependence of the motions involved...