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Analysing intermediates of a CO2 insertion reaction using simultaneous operan...
Atmospheric levels of CO2 are increasing at uncontrolled levels and as such methods of CO2 utilisation are being researched. A key reaction for this purpose is the coupling of... -
Investigation of a novel mechanism of antibiotic resistance
This dataset has no description
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INS on H2 adsorbed in microporous L-Isoleucyl-L-valine.
We intend to perform an inelastic neutron scattering experiment on para-H2 adsorbed in L-Isoleucyl-L-valine (IV) microporous systems using the TOSCA spectrometer. IV is one of a... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Adsorption of hydrophobin at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how another globular protein hydrophobin adsorbs at the oil/water interface by... -
The Mechanism of Bam Mediated Outer Membrane Protein Folding
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival,from providing basic physiological functions, to impairing virulence and... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Further studies of the Mg(BH_{4} )_{2} and parahydrogen
We found evidence of solid para-hydrogen absorbed in Mg(BH_{4} ){2} up to temperatures of 195 K. Para hydrogen was dosed in Mg(BH{4} )_{2} at 50 K. A series of dosings were... -
Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Inter...
In this work we explore how to use neutron reflection to study protein adsorption at the oil/water interface. Inter is preferred because we have built technical capability on... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Understanding light-induced changes to the miscibility of polymer/fullerene s...
Polymer/fullerene blends represent the most common form of organic solar cell. This proposal forms part of a wider effort in which our motivation is to complement solar cell... -
Investigating a Dextrin-Phospholipase A2 Conjugate as a Trigger for Polymer E...
Recent research has demonstrated the potential of nanosized delivery systems for routine use in many diseases, eg cancer, viral diseases and rheumatoid arthritis [1,2], due to... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
Self-assembling antimicrobial peptides: interactions with model lipid membranes
We propose to investigate antimicrobial peptides that self-assemble into well-defined nanostructures. Previous SAXS results have shown that the peptides form rather robust... -
Introducing the O-antigen into Bacterial Outer Membrane Models
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
In-situ Inelastic Neutron Spectroscopy Studies Of Magnesium Tetrahydroborate ...
The development of high energy density and high efficiency hydrogen storage materials is widely considered to be one of the most challenging barriers to the adoption of fuel... -
IN-SITU INELASTIC NEUTRON SPECTGROSCOPY STUDIES OF METAL-HYDRIDE HYDROGEN STO...
Hydrogen storage is considered to be one of the principal technological barriers in the transition towards a hydrogen-based economy. In this proposal, we plan to look at the key... -
The Interaction of Small Cationic Amphiphillic Antimicrobial Proteins with Fr...
Protein-membranes interactions are fundamentally important to biological function. We have developed advanced models of the Gram negative bacterial outer membrane and have... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
