31 datasets found

The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with...

Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of...

The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the...

In this experiment we aim to investigate, using neutron reflectometry in combination with contrast variation, the intermolecular interaction between the nucleic acid, calf...

Recent research has demonstrated the potential of nanosized delivery systems for routine use in many diseases, eg cancer, viral diseases and rheumatoid arthritis [1,2], due to...

The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface....

Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for...

The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be...

Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a...

We have recently improved the stability and coverage of free standing bilayers (FSB) by the use of a supporting thiolipid layer on gold. The system has been investigated on...

Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the...

Cell-nanoparticle interactions are complex, involving several specific and non-specific intermolecular forces between a wide range of particulate and molecular species . There...

Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular...

Clupeine is isolated from herring and is an example of a protamine, which are cationic antimicrobial peptides occurring in the sperm cells of some fish. Protamines are active...

Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading to interfacial adsorption and solution nano-aggregation....

The main objective of the present work is to complete some work aimed at gaining an understanding of the interaction of phospholipid membranes containing the neutral helper...

In polymer-fullerene based photovoltaic systems the phase behaviour of the blends is poorly understood and remains a fundamental stumbling block to improvements in device...

Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug...

Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long...