8,732 datasets found

The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving...

The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the...

Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is...

We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading interfacial adsorption and solution nano-aggregation....

Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show...

In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,...

We have been investigating the influcence of the cationic staphylococcal lipid lysyl-phosphatidylglycerol (L-PG) on bacterial resistance to antimicrobial peptides (AMPs). Using...

Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug...

We propose to investigate the interfacial adsorption of a series of water-soluble single chain PC surfactants using neutron reflection, focusing on assessing the effects of...

With the beamtime requested we plan to employ small-angle neutron scattering (SANS) to study novel nanocolloidal drug carriers prepared using lipids, surfactants and...

We wish to investigate the pH-dependence of the strong interfacial interaction of 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) with poly(silicic) acid at the air-water...

Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how another globular protein hydrophobin adsorbs at the oil/water interface by...

Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we...

We propose to use neutron reflection to study the interfacial adsorption of 2 novel bispecific therapeutic antibodies at the silicon oxide/water interface. To enpower each of...

We have previously studied the adsorption of anti-beta-hCG at the hydrophilic silicon oxide/water interface and the subsequent binding by antigen hCG. We propose to extend this...

Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection....

This proposal constitutes part of our ongoing study towards understanding the adsorption of collagen based polypeptide and its interaction with ionic surfactants at the...

Short peptide sequences such as KLVFFAE form well defined beta sheet structures. Their further templating through hydrophobic interactions and hydrogen bonding is the principal...

Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the...