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How N-acyl amino acid surfactants adsorption at the air/water interface helps...
N-acyl amino acids are promising anionic amphiphilic molecules, which consist of a linear aliphatic chain (hydrophobic tail) and an amino-acid residue (polar head). Although... -
The role of tryptophan in puroindoline/purothionin cooperative binding to bio...
The puroindoline (PIN) and purothionin (PTH) families of polypeptides both occur in wheat and are implicated in antipathogenic defence mechanisms, and of interest for potential... -
Mesostructured titania films from ethanolic solutions
In this proposal we wish to continue our current work on mesostructured inorganic films in largely ethanolic solutions, containing limited amounts of water. Transition metal... -
Neutron Reflectivity Study of Protein Adsorption onto Cell Membrane-inspired ...
We grafted 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer brush from the silicon wafer surface through Cu (0) mediated controlled radical polymerization (CuCRP) to mimic... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Surface adsorption of lipopeptides: interfacial layer structure
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims at elucidating how bile salts (BS) structure influences their interfacial behaviour and their impact on fat digestion. Neutron reflectivity (NR) is the... -
Organization of mitochondrial membranes upon oxidative stress: Impact on apop...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Developing a generic gravimetric method to determine the composition of films...
We propose to develop a new and generic, multi-probe technique to characterize the mass, and changes in mass, of material probed in a NR experiment. This methodology will be... -
Segregation of Zwitterionic Surfactants in PVA Film and Influence of Compatib...
Migration and segregation of small molecules in complex polymer matrices is relevant to a huge range of industrial problems which we aim to address via a coordinated series of... -
Surface composition in the physical developer process for latent fingerprint ...
Physical developer (PD) is a latent fingerprint development technique that is highly effective on paper and related surfaces, notably banknotes. The process exploits a redox... -
Adsorption of Sodium Polyacrylate onto a-Alumina
In this proposal we investigate the adsorption of the key dispersant additive, sodium polyacrylate, used in colloidal systems using neutron reflection on aluminium oxide, with... -
Application of direct inversion to magnetic contrast datasets.
We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This... -
Protein density profile near protein-resistant self-assembled monolayers: Sen...
Oligo(ethylene glycol) self-assembled monolayers (SAMs) effectively prevent the adsorption of proteins from biological media. Despite the importance of this effect for... -
Probing the spatial distribution of fluorophores entering nanoscale pores in ...
We wish to make specular NR measurements on fluorophore functionalization of amine-functionalized polypyrrole (PPy-NH2) films. The critical issue is film penetration of solution... -
Unusual structural change in geminis above the critical micelle concentration
gemini surfactants are essentially two surfactants joined by a linking chain. We have extensively explored cationic geminis at the air/water interface and they exhibit a range... -
The effect of phospholipid on the adsorption of HSA at a solid surface
As part of a project concerning the fate of nanoparticles in the body we have been studying the kinetic and competitive (or cooperative) aspects of protein adsorption. HSA is... -
Heusler Alloy Thin Films for Spin Seebeck Devices
The spin Seebeck effect is a relatively new phenomenon that could be harnessed for waste heat recovery. Its advantages lie with a new device architecture (compared to... -
Amide monolayers at the polymer melt air interface
This proposal seeks to identify and characterise the adsorption of primary linear amides that adsorb to the surface from the bulk of a polymer melt. These layers are... -
Proving ground-state ordering in Artificial Spin-Ice systems formed by sub-10...
The main purpose of the experiment proposed here is to study the effects of thermalisation on Artificial Spin-Ice (ASI) systems formed by nanomagnets with sub-100 nm lateral...
