67 datasets found

We have begun an experimental program to investigate the denaturing of DNA, using scattering techniques, to test statistical mechanical models for the moelcule. It is believed...

We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing...

DNA is an extremely versatile building material for the development and assembly of functional nanostructures and nanodevices. There are numerous examples of DNA based...

DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We...

We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS...

The interaction of ionizing radiation such as X-rays with biological samples causes damage to the samples. Recent work from our group with various protein crystals, peptides and...

The aim of the present neutron reflectivity proposal is to obtain stereochemical and kinetic information studying the thermo-lyotropic behaviour of the lipid mixture DOPC-DDAB...

We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of...

Gene (nucleic acid) delivery to the cytosol or nucleus of a cell is, without the aid of a suitable delivery system, an inefficient process. Here the interaction of a defined...

It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic...

Cancer is a growing health problem worldwide, and thus the development of effective chemotherapeutic approaches is crucial for improving human health. Much effort has been put...

We have recently developed novel ternary lipopolyplex vectors (i.e. gene delivery vectors containing cationic lipid, plasmid DNA and a cationic peptide) in which, for the first...

Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the...

Online repository of DNA sequence files regarding a new chassis strain of Zymomonas mobilis.

The database hosts a dense diversity of arthropod species that are pests of different cultures throughout the world, as well as their natural enemies plus some species of...

The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random...

The participants in this cohort are individuals with breast cancer and metastatic disease coming to the Department of Oncology in Lund for treatment since 2003. The data...

In this unique Swedish study, which started in September 2008, all new and prevalent cancer cases in southern Sweden are included to create a family history data bank. All...

The cohort was recruited among accompanying spouses of cancer patients at the Oncology Clinic at Lund University Hospital. The study will be used as a reference population in...

ANDIS is a combined research and quality assurance project with the long term aim of introducing precision medicine in diabetes. In connection with a visit to your doctor or...