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The Interaction of wild-type and mutant Puroindoline B with Model Bacterial M...
Bacterial and fungal infections of cereal crops pose a considerable risk to global food security. Typically plant pathogens are controlled through the use of chemical agents... -
Comparative Interaction Studies of Antimicrobial Agents on Floating Asymmetri...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
Impact of surfactant interactions on fate of marine aerosols: NO3-initiated o...
Mixed films of palmitic acid (PA) and galactocerebrosides (GCB) a proxy for marine aerosol exhibit attractive interactions due to H-bonding of galactose and carbonyl head... -
Investigation of zwitterionic surfactant, Ca2+ and bio-polymer interactions
We are currently investigating the formation and structure of surfactant-templated polymer films comprised of cat-anionic surfactant mixtures and a variety of polymers. As we... -
Calcium mediated interaction between siRNA and phospholipid bilayers: the eff...
The main objective of the present study is to gain an understanding of the nature of the interaction of ¿phospholipid membranes¿ with small, interfering RNA (siRNA) in the... -
Phase diagram of LAS molecule: SANS investigation into surfactant and lipid m...
This proposal would like SANS time to better understand the LAS phase diagram. This has been prompted by recent experiments which show the system is not fully understood under... -
Model anionic/non ionic surfactant adsoption at the interface below room temp...
An experiment performed on INTER last year found extreme non ideal mixing between C12E8/SLES3 at the air water interface: this feature became more extreme as the temperature... -
The Interaction of Small Cationic Amphiphillic Antimicrobial Proteins with Fr...
Protein-membranes interactions are fundamentally important to biological function. We have developed advanced models of the Gram negative bacterial outer membrane and have... -
Impact of multivalent counterions on surfactant self-assembly
We request SANS beam time on LOQ to study the impact of multivalent counterions on the micellisation of alkyloxyethylene sulfate surfactants and alkyloxyethylene sulphate /... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
Oxidation of gram-negative cell-wall proxy with OH radicals - kinetics and me...
Hydroxyl radicals may be used as disinfection agent in the advanced oxidation processes or tertiary treatment of waste and occasionally drinking water. In this exploratory work,... -
Neutron reflectivity studies of the interaction of amphotericin with model ce...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Sustainable polymeric deposition aids
This is a new programme of work and a collaboration between CCLRC, Oxford, Unilever and Manchester. It is concerned with polymer aided deposition to solid substrates, using... -
The impact of polyelectrolytes on surfactant adsorption onto cellulose surfaces
Studying surfactant and mixed surfactant adsorption on model solid surfaces, which mimic real surfaces such as fabrics, hair and skin, is starting to provide a real insight into... -
Evolution of complex surface structures in LAS / nonionic surfactant mixtures
This proposal is part of a broad programme of collaborative research between RAL / Oxford and Unilever, using predominantly scattering techniques to investigate the nature of... -
Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Po...
In this proposal, we request beamtime to study the very unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate potassium and ammonium salt (K(AOT)... -
Adsorption of Sodium Bis-(2-ethylhexyl)phosphate on a-Alumina
In this proposal we investigate the adsorption of a key additive and functional group used in lubrication and wear applications using neutron reflection on a metal oxide... -
The Mechanism of Bam Mediated Outer Membrane Protein Folding
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival,from providing basic physiological functions, to impairing virulence and... -
Using Magnetic Contrasts to Establish the Mechanism and Kinetics of Lipid Fli...
In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied...