Hydrogels from biopolymers are attracting increasing attention for a range of biomedical applications, but the lack of structural understanding hinders the development of new applications. Our work focuses on hydrogel scaffolds based on fish gelatin, where the networks are either physical, through the reversible formation of triple helices, and/or chemical, by the use of an enzymatic process. Our objectives are to correlate the bulk (or macro) properties of the gels to their microstructure, and link this knowledge to their performance to regenerate cells. We propose to use SANS to achieve an understanding of the nano-scale structure of the networks. Properties-structure relationships are fundamental to a formulation rationale and this work will give us precious insight into the gels architecture and help promote the use of neutrons in the area of biomaterials.