We conducted a year-long aquarium experiment with Lophelia pertusa (synonym Desmophyllum pertusum) under projected end-of-century conditions, investigating the combined effect of differences in pH (8.1 and 7.7), temperature ( 9 degrees Celsius 9 degrees Celsius 9 degrees Celsius and 12 degrees Celsius 12 degrees Celsius 12 degrees Celsius ), oxygen concentration (100%and 90%) and food supply (100% and 60%) on coral survival, growth, respiration rates, skeletal dissolution and energetic reserves.This dataset is included in the OA-ICC data compilation maintained in the framework of the IAEA Ocean Acidification International Coordination Centre (see https://oa-icc.ipsl.fr). Original data were downloaded from the PANGAEA dataset (see Source). In order to allow full comparability with other ocean acidification data sets, the R package seacarb (Gattuso et al, 2024) was used to compute a complete and consistent set of carbonate system variables, as described by Nisumaa et al. (2010). In this dataset the original values were archived in addition with the recalculated parameters (see related PI). The date of carbonate chemistry calculation by seacarb is 2026-06-17.