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Influence of Alkyl Chain Fluidity on the Membrane Binding Activity of Cationi...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improves patient compliance and can provide a release for long... -
Interfacial adsorption of monoclonal antibodies and antigen binding
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
The Formation of Ion Channels in Phospholipid Bilayers by Puroindoline-a
Puroindolines are basic, cysteine rich proteins of ~13KDa, which have attracted significant interest due to their role in determining the endosperm texture of Wheat and seed... -
Heterogeneous protein exchange at the solid/liquid interface using deuterated...
The formation of protein layers on surfaces is important for medical implants and for the consequences of the ingestion of nanoparticles. In the body, a surface is exposed to a... -
Membrane-stacking Properties of Mutant Myelin Proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Temperature Effects and Kinetics of Thiolipid Adsorption to Gold Surfaces
We have a programme investigating the structure and function of protein scaffolds oriented on gold surfaces using sulfur chemistry for attachment. The aim is to direct the... -
Interplay of apoptosis regulating Bcl-2 proteins with mitochondrial membranes...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Influence of the polarity of plasticizer and degree of hydrolysis of Poly-Vin...
Migration of small molecules to, and across the surface of polymer matrices is a little-studied problem with important industrial applications. PVAc films are of industrial... -
Polyoxometallate surfactant adsorption at solution surfaces
Polyoxometallates (POM) are well defined transition metal clusters with a range of interesting catalytic, magnetic and optical properties. To make efficient use of these... -
Neutron reflection from surface-induced nana-stratified He-3/He-4 mixtures
It is proposed to use neutron reflectometry to study surface-induced nano-stratification of 3He-4He mixtures in the ultra-low temperature limit. The experiment promises to... -
Effect of Phosphatidylserine lipids on Tissue Factor structure and function i...
Tissue Factor (TF) is the membrane protein responsible for the initiation of the blood coagulation process [1]. In case of a vessel injury, the TF is exposed to the blood stream... -
Surfactants at the metal-oil interface
The lubrication of surfaces by oils is a key aspect of many academic and industrial problems with significant financial implications. We would like to study, for the first time... -
Outer membrane mimics using novel thiol-PC
We have recently shown that dense monolayers of PC can be assembled on gold surfaces using a new omega thiol PC from Avanti. This has two advantages over our previous methods.... -
Adsorption Kinetics and Structure of Silicatein Mediated Silica Films
The fabrication of composite coatings based on silica with well defined physical properties represents a promising new approach to fine-tune mechanical, optical, electronic, and... -
Measuring the reflectivity from molten chocolate sandwiches
Molten chocolate is a dense suspension of solids (mainly sugar) in oil, to which surfactants have been added to improve the flow properties, either during manufacture or in the... -
Adsorption versus aggregation; Particles and surface of matching material
The balance between particle-surface and particle-particle interactions is entropically driven. We would like to investigate wherever a multiplayer layer adsorption on a... -
Enzyme-catalysed templating of biosilica
Summary. Silicatein in marine sponges catalyses the condensation of silica but the mechanism of layer-by-layer growth of the silica spicule is unknown since sufficient... -
Studying the lateral organisation of mixed phospholipid bilayers by diffuse n...
Off-specular neutron reflection is potentially a powerful technique for studying the lateral organisation of phospholipid bilayers. However, this has not yet been demonstrated.... -
Interfacial Adsorption of Soluble Amino-Acid Based Surfactants in Mixtures wi...
Amino acid based surfactants have been known for many years, but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from... -
Adsorbtion from nematic mixtures
The aim is to measure the preferential adsorption of one component in a nematic mixture. The base is 4-pentyl 4¿- cyanobiphenyl (5CB) and it is doped with 4-pentyl 4¿-...