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Silk fibrillogenesis: Morphology, structure and hydration of the intermediate...
At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of... -
Building a model for gastric mucins
Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection.... -
Non-equilibrium kinetics in highly interacting polymer mixtures
We seek to investigate the non-equilibrium phenomena of a model polymer mixture by time-solved SANS and temperature jump experiments within (a) one-phase region and (b) one to... -
SANS from photoconductive hydrogel mixtures and their gelators.
Hydrogels are formed from a self?assembled network of fibres made up of small molecules (gelators) trap and hold water at just 1% by weight, or less, from the solution they are... -
Aggregation behaviour of aqueous hairy rod conjugated polyelectrolyte/surfact...
Small angle neutron scattering (SANS) will be used to characterise the structures of aggregates formed between the anionic conjugated polyelectrolyte... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Phase Separation in Organic Photovoltaic Cells
Organic photovoltaic (OPV) cells have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art solution-processed... -
Nanoscale Phase Separation in Organic Solar Cells and Its Impact on Device Pe...
Solid-state Organic Solar cells (OSCs) have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art... -
Probing membrane localisation of molecular rotors (SANS)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Revealing the Structure behind the Synergistic Phase Behavior of the Ternary ...
The aim of this collaborative proposal is to unravel micro- and nano-structures underlying unusually high solution viscosities from mixed surfactant systems. SANS is a unique... -
Coordinated, Recoiling Molecules Tethered by Hydrogen Bonding: Ammonia in Zeo...
We request 5 days on IRIS to investigate the hindrance to molecular rotation of ammonia in a zeolite framework due to hydrogen bonding interactions. This is a tied proposal to... -
SANS studies of Amphotec (aggregates of amphotericin-cholesteryl sulfate)
The anti-fungal agent amphotericin B (AmB) can be administered to patients in aqueous solution complexed with cholesteryl sulfate (CS), and this formulation helps to minimise... -
Using SANS to understand the structure and behaviour of surfactants in chocolate
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
Micellization in glycerol:choline chloride deep eutectic solvent
Deep Eutectic Solvents (DES) are molecular mixtures with melting points below room temperature. DES share many features of ionic liquids (low vapour pressure, adjustable... -
SANS Investigation on Packing Structure of Proteasome Activator 28
Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large... -
Water dynamics in porous PTFE membranes for water purification
This is a resubmitted proposal in a new project on water purification by membrane distillation. With this technology liquid water is excluded from passing the separating... -
Intercalation of Ciprofloxacin into Lithium - Fluorohectorite at acid and bas...
Using quasielastic neutron scattering (QENS) we will investigate the intercalation of Ciprofloxacin (CIPRO) into the synthetic clay Lithium Fluorohectorite (LiFh) to... -
SANS study of the structure of surfactant stabilised Pt and Ru nanoparticles
Surfactants have been used to bind and disperse Pt and Ru nanoparticles during their synthesis. In this work, we propose to use SANS to determine the thickness and packing... -
Composite Electrospun Fibres based on Food waste
Thus proposal seeks to explore the nature of electrospun composite fibres where the polymeric material contains a substantial quantity of biopolymer obtained from food waste -... -
Probing the structure of polymer stabilised foams
Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent...