-
Molecular architecture of novel, trichain-containing vectors for gene delivery
We have recently developed novel ternary lipopolyplex vectors (i.e. gene delivery vectors containing cationic lipid, plasmid DNA and a cationic peptide) in which, for the first... -
Structure of Cellulose Nanofibril Gels with Different Surfactants
This proposal is part of a project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils and small amounts of additives, such... -
The structure of the Bam complex, the Gram-negative outer membrane protein fo...
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival, from providing basic physiological functions, to impairing virulence and... -
The action of membrane lytic compounds on model membranes.
The study of antifungal and antibacterial action is of great interest and there are still many unknowns concerning the action of membrane lytic materials, and the way that... -
Polymer displacement by surfactant at colloidal interface
The interactions of neutral polymers with surfactants have a key role in detergency and are systems of current academic and commercial interest. Here, we propose to study the... -
Effect of drug on the micelles formed by ionic surfactants
The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles... -
Cationic & Nonionic Micelles in Deep Eutectic Solvents
Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. DES share many of the features of ionic liquids (low... -
Fundamentals of Nanotoxicity: The Role of Nanoparticles in Lowering the Energ...
Despite the increasing use of nanoparticles (NPs), our current knowledge of how NPs interact with the human body or the environment remains limited. Of a number of mechanisms, a... -
Characterisation of Precious Metal Hydrous Oxide and Hydroxide Compounds
Approved proposal under the ICRD Scheme Proposal ICRD0003 -
Characterization of heterogeneous solvent structure in a carbon capture fluid
We propose to use neutron scattering experiments to gain molecular level insight into an intriguing liquid structure observed in a water-free CO2-capture solvent. Switchable... -
Nanosuspsomicroemulsions: nanosuspension stabilty
At Kings College London we have recently developed a novel combination formulation, a nanosuspsomicroemulsion (NSME), comprising of a microemulsion (ME) containing one drug and... -
Search for magnetic domains in frustrated magnet CaFe2O4
We propose to study the temperature dependence of the size and shape of the magnetic domains believed to exist in CaFe2O4 - a frustrated triangular antiferromagnet. Our diffuse... -
Structure of Cellulose Nanofibril Gels
This proposal is part of a new project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils with small amounts of salt or... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Life without water: The role of intrinsically disordered proteins under condi...
When cells are subjected to stress, such as drying, globular proteins are observed to unfold and irreversibly aggregate. Certain intrinsically disordered proteins (IDPs) do not... -
Probing the structure of polymer stabilised foams
Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent... -
Composite Electrospun Fibres based on Food waste
Thus proposal seeks to explore the nature of electrospun composite fibres where the polymeric material contains a substantial quantity of biopolymer obtained from food waste -... -
SANS study of the structure of surfactant stabilised Pt and Ru nanoparticles
Surfactants have been used to bind and disperse Pt and Ru nanoparticles during their synthesis. In this work, we propose to use SANS to determine the thickness and packing... -
Intercalation of Ciprofloxacin into Lithium - Fluorohectorite at acid and bas...
Using quasielastic neutron scattering (QENS) we will investigate the intercalation of Ciprofloxacin (CIPRO) into the synthetic clay Lithium Fluorohectorite (LiFh) to... -
Water dynamics in porous PTFE membranes for water purification
This is a resubmitted proposal in a new project on water purification by membrane distillation. With this technology liquid water is excluded from passing the separating...