23 datasets found

This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an...

At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of...

Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection....

Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce...

Measurements are required for Sans2d resolution checks and also the overlap of the two Sans2d detectors. Proposal submitted to panel and they deemed it should be done as...

Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they...

Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...

Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds...

The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival, from providing basic physiological functions, to impairing virulence and...

In this proposal we will investigate hypothesized asymmetric diffusion of water into lipid cubic (QII) phases. This asymmetric diffusion, which is relevant to the behavior of...

In a one-pot synthesis, we are able to produce spherical gold nanoparticles capped with antibiotics, without the use of other chemicals by using the antibiotic as the reducing...

Approved proposal under the ICRD Scheme Proposal ICRD0006

Endocytosis plays a central role in allowing the selective transport of molecules, via membrane-derived vesicles, into cells. Vesicle formation is controlled by a complex...

Recently, it is reported that the functional nucleosomes, CENP-A nucleosome, H2A.Bbd nucleosome and hexasome, which include variant histone cores, could have flexible and mobile...

Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...

Plasmonic nanoparticles (NPs) are emerging as a promising category of materials, which might find applications in optical storage of information, optical wave guiding,...

Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane...

This proposal is part of a new project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils with small amounts of salt or...

The sun is an abundant and cheap source of energy, harnessing it as storable fuel has the potential for a large societal impact. Organic photoelectrodes (PEs) formed from low...

Despite the increasing use of nanoparticles (NPs), our current knowledge of how NPs interact with the human body or the environment remains limited. Of a number of mechanisms, a...