Asymmetric diffusion of water into bicontinuous cubic lipid nanomaterials using D2O / SANS

DOI

In this proposal we will investigate hypothesized asymmetric diffusion of water into lipid cubic (QII) phases. This asymmetric diffusion, which is relevant to the behavior of QII phases in drug delivery and mesoporous metal templating, was hypothesized fifteen years ago; while there are several pieces of data indirectly supporting the suggestion, we propose to produce the first direct experimental evidence using small-angle neutron scattering (SANS) with H2O / D2O contrast.

Identifier
DOI https://doi.org/10.5286/ISIS.E.79108082
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/79108082
Provenance
Creator Dr Nick Brooks; Dr James Doutch; Dr Adam Squires; Dr Ann Terry; Mr Ben Eves; Miss Eleonore Mason
Publisher ISIS Neutron and Muon Source
Publication Year 2019
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Chemistry; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering; Natural Sciences
Temporal Coverage Begin 2016-05-09T08:00:00Z
Temporal Coverage End 2016-05-11T08:00:00Z