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Structural examination of self-assembled floating membranes below grafted lip...
Robust, reliable, and protein-free bacterial membrane mimicking systems compatible with the high through put screening techniques will largely facilitate the discovery of new... -
Interaction of an antimicrobial peptide from Lactobacillus gasseri supernatan...
A short peptide, composed of 12 amino acids (EFVFVAHAVPVM), presenting a strongly hydrophobic character, was recently isolated from Lactobacillus gasseri supernatant (AMP12).... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
This dataset has no description
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Examination of Free Floating Models of the Gram-Negative Bacterial Outer Memb...
This dataset has no description
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Electrostatic Interactions between Floating Bilayers and Thiol Coated Interfa...
Bilayers which float below a self-assembled monolayer (SAM) coated solid support represent one of the most advanced membrane mimetics. Recently (RB 1720155) we assessed the... -
Oxidation of gram-negative cell-wall proxy with OH radicals - kinetics and me...
Hydroxyl radicals may be used as disinfection agent in the advanced oxidation processes or tertiary treatment of waste and occasionally drinking water. We very recently oxidised... -
Seizing Membrane Proteins - Cytochrome P450 Reductase in Nanodiscs
This proposal seeks to shed light on the functional and structural characteristics of a specific membrane protein - cytochrome P450 reductase (abb. POR) - part of the cytochrome... -
Probing membrane localisation of molecular rotors (NR)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Probing the interactions of chitosan with lipid bilayers to elucidate its ant...
Chitosan is a linear polysaccharide that is biocompatible and biodegradable. Chitosan has a number of unique chemical and biological features including its cationic nature and... -
Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic lipid bil...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Modification of an adsorbed cationic layer by anionic surfactants below the CMC
In this proposal, we request beamtime to study the unexpected behaviour of a strongly bound bilayer of the cationic surfactant didodecyldimethylammonium bromide on the anionic... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
Optimisation of Experimental Conditions for the Study of Anionic Self-Assembl...
We have developed a Self-assembled floating supported membrane sample system comprised of unsaturated phospholipid bilayers held ~1nm from a PEGylated charged alkane thiol SAM... -
Co-adsorption and competitive adsorption of eggshell membrane polypeptide aga...
In this work we explore how to use neutron reflection to study the interfacial adsorption from a natural eggshell membrane polypeptide at the oil/water interface. We will then... -
Manipulating surface adsorption of SLES surfactants using temperature
Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we... -
Interaction of Surfactant with Model Lipid Membranes: Influence of Surfactant...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long... -
Oxidation of a bilayer of DOPC by aqueous ozone - a chemical, kinetic and mec...
Mineral aerosol in the atmosphere is a major part of the Earths aerosol budget. Organic films on these aerosols affect the aerosols ability to promote cloud formation and... -
The calcuim mediation interaction of DNA with monolayers of DSPC and DOPE
The main objective of the present work is to complete some work aimed at gaining an understanding of the interaction of phospholipid membranes containing the neutral helper... -
Effect of membrane fluidity for novel dendrimer drug interaction and uptake m...
Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel... -
Understanding the Affect of Lipid Tail Saturation on Anaesthetic Interaction ...
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers...
