48 datasets found

Oxidation of atmospheric aerosol can produce cloud condensation nuclei capable of changing the reflectivity and lifetime of clouds. The oxidation of organic film on atmospheric...

We have a programme investigating the structure and function of protein scaffolds oriented on gold surfaces using sulfur chemistry for attachment. The aim is to direct the...

The aim of our experiment is to understand the link between interfacial width and the photophysics at the interface to the operation of a polymer solar cell. We propose to...

Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their...

Engineered nanoparticles (NPs) found large application in medicine as theranostic materials for the diagnosis and therapy of many diseases. The understanding of the interactions...

Following our previous study of adsorption of globular lysozyme and BSA at the oil/water interface by neutron reflection, we continue to explore how unfolding of globular...

Cyclic peptide-polymer nanotubes can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. As such, understanding how...

Off-specular neutron reflection is potentially a powerful technique for studying the lateral organisation of phospholipid bilayers. However, this has not yet been demonstrated....

The aim is to measure the preferential adsorption of one component in a nematic mixture. The base is 4-pentyl 4¿- cyanobiphenyl (5CB) and it is doped with 4-pentyl 4¿-...

Plant-derived biosurfactants of the group of saponins offer an attractive alternative to synthetic surfactants because of their unique foaming and emulsifying properties...

In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied...

Oxidation of lipid membranes is widely known to play a crucial role in many cellular processes and pathological conditions such as apoptosis, inflammation, infection, or sepsis,...

The proposed experiments will investigate conformational changes of the 18kDa translocator protein (TSPO) in a lipid bilayer using neutron reflectometry at the solid-liquid...

Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported bilayer films. In this proposal we...

N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered...

Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,...

Advantages of using organic materials as the active layer in photovoltaics include their suitability for low cost and large area processes and their mechanical flexibility. In...

The oxidation of membrane lipids by reactive Oxygen Species, ROS, is implicated in cell apoptosis, cancer and ageing. We have performed preliminary experiments studying the...

We ask for 8 days of beam time on CRISP to study the absorption and desorption of hydrogen and deuterium in Ti/Mg/Pd trilayer samples. Our specific objective is to understand in...

The cell membrane is a very important structure in biology and many laboratory based model systems have been developed to study it using biophysical techniques. Our particular...