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Formation of asymmetric free-standing bilayers with lipopolysaccharide in the...
We have recently improved the stability and coverage of free standing bilayers by the use of a supporting thiolipid layer on gold. The system has been investigated on POLREF and... -
Adsorption of Monoclonal Antibodies at the Solid/liquid Interface
We propose to use neutron reflection to study the interfacial adsorption of 2 novel bispecific therapeutic antibodies at the silicon oxide/water interface. To enpower each of... -
A study of hole injection efficiency for a model conjugated bilayer system
Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our... -
Interaction of amino acid based biosurfactants with model lipid bilayers
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Using Magnetic Contrasts to Establish the Mechanism and Kinetics of Lipid Fli...
In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied... -
Non-planar exchange bias in a hard magnetic FePt/FePt3 epitaxial bilayer
We plan to perform polarized neutron reflectometry (PNR) on an epitaxial FePt(10nm)/FePt3(60nm) bilayer grown on a MgO(110) substrate. One particularity of this exchange bias... -
Magnetic contrast NR to resolve MscL opening under PXG challenge
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock, but, as with all ion channels, they have the potential to act as an Achilles heel,... -
Binding of DNA to Model Membranes in the Presence of Ca2+ Ions and a Membrane...
The aim of the present work is to gain an understanding of the interaction of DNA with the phospholipid bilayers. The effect of different forms of DNA, the presence of divalent... -
Evolution of complex surface structures in LAS / nonionic surfactant mixtures
This proposal is part of a broad programme of collaborative research between RAL / Oxford and Unilever, using predominantly scattering techniques to investigate the nature of... -
A study of hole injection efficiency for a model conjugated bilayer system
Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our... -
Self-Organisation of Phospholipids on Au Electrodes
This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
NTC2015
This dataset has no description
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Anomalous Layer at a Nematic-Air Interface
The aim is to establish the nature of the surface layer of 8CB at the nematic-air interface by measuring neutron reflection from three differently deuterated versions of 8CB.... -
Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Temperature dependence on mangetic excitations from the high Tc cuprate BSCCO
We plan to continue inelastic neutron scattering measurements on the high Tc cuprate superconductor BSCCO with optimum doping. In the proposed experiment, we will have about 40... -
DPPC bilayer oxidation by aqueous singlet oxygen
Oxidation of membrane lipids by Reactive Oxygen Species, ROS, in cells may impact ageing, cell apoptosis and cancer. We propose to use our skills obtained studying the oxidation... -
Phase retrieval for non-trivial systems
Neutron reflectometry (NR) is a very powerful technique for the study of thin layers. It is able to measure composition, thickness and roughness and is a very penetrating... -
The Orientation and Conformation of an Enantiomeric Pair of 310 Helical Pepti...
We wish to investigate the interactions between peptide mimics of peptaibols, a highly active class of natural antimicrobial peptide, and membranes. In particular we are... -
Neutron Reflectivity Study of Antimicrobial Peptides Interacting with Lipopol...
The outer membrane (OM) of gram negative bacteria is mainly constituted of highly polydisperse and amphiphilic lipopolysaccharide (LPS), an endotoxin which is accompanied by...
