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Joint Diamond/ISIS proposal 22078
The basis of a biological cell membrane is a lipid bilayer containing functional proteins. Its purpose is to form a selective barrier that separates the aqueous fluids inside... -
The Effect of the Head Group on Multilayering of Alkanoic Alkyl Ester Sulphon...
We have shown that under certain conditions multilayer adsorption of surfactants occurs at the air-water interface. in which case the system becomes a powerful wetting agent (it... -
Impact of Stereochemistry and Diamine Structure on Absorption of Constructed ...
Chiral gemini surfactants containing stereogenic centers and two amphiphilic moieties, not only maintain the chiral properties, but also exhibit stronger aggregation properties,... -
Interplay of apoptosis regulating Bcl-2 proteins at mitochondrial membranes u...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). This pathway is a major regulator in cell... -
Interaction of Surfactant with Model Lipid Membranes: Influence of Surfactant...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long... -
Neutron reflectivity studies of the interaction between a novel antimicrobial...
A Unilever proprietary technology has been shown to inhibit biofilm growth and development, and is also found to possess antimicrobial activity, effective both as a... -
Polyoxometallate surfactant adsorption at solution surfaces
Polyoxometallates (POM) are well defined transition metal clusters with a range of interesting catalytic, magnetic and optical properties. To make efficient use of these... -
The Impact of Multivalent Counterions on the Surface Adsorption of the Anioni...
Surface multilayer formation provides great potential for the tuning and optimising surface wetting properties and applications such as lubrication, drug delivery. Normally... -
Protein nanosheets assembled structures at the air-water interfaces for cell ...
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Neutron reflectivity studies of the interaction of Amphotericin B with biomim...
Bio-surfactants that can be harvested from micro-organisms are of particular interest, because these can potentially be harvested in high yield and at low cost. In this category... -
Fluorocarbon/ Hydrocarbon Mixed surfactant monolayers for fire-fighting appli...
The aim is to use Neutron Reflectivity (NR) to gain essential information on the adsorption properties of fluorocarbon (FC)/ hydrocarbon (HC) mixtures in commercial... -
How does oxidative damage change peptide membrane insertion?
The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells... -
Protein nanosheets assembled structures at the air-water interfaces for cell ...
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Packing structural conformation of (H/D) nanogels at the air/water interface
The interfacial behaviour of thermoresponsive N-propylacrylamide (NPAM) based nanogels differs from solid nanoparticles because of the soft structural character. These nanogels... -
How does tendency to adopt different secondary structures from antimicrobial ...
This work aims to exploit the unique capability of neutron reflection to examine how 2 antimicrobial lipopeptides that tend to adopt different secondary structures bind to model...