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SANS study of lipid-based nanocarriers as inhaled drug delivery systems for a...
The present project aims to achieve a more detailed structural characterization by SANS of Solid Lipid Nanoparticles (SLN) and liposomes in a perspective of an inhaled anti... -
Rheo-SANS on calcium caseinate under shear and heat
Producing meat analogue instead of real meat is one effective way to reduce carbon emission and improve animal welfare. Calcium caseinate is a prominent candidate for making a... -
Structural and mechanistic study of nanocapsule / hydrogel composites for dru...
The targeted delivery of non-water soluble drugs for applications such as cancer remains a major challenge. Nanocapsules are new materials that can act as a depot for such drugs... -
Structure and mobility of surfactant additives in PDMS resin
Polysiloxane materials are commonly used in marine coatings due to their inherently low surface energy and flexibility which makes them suitable base materials for foul release... -
On the structure and composition of non-lamellar lipid-based liquid crystalli...
Liquid crystalline particles consisting of glycerol dioleate (GDO) / soy phosphatidylcholine (SPC) mixture and stabilised by polysorbate 80 (P80) have proven to be suitable as... -
Origin of co-nonsolvency, based on the Flory-Huggins interaction parameters o...
Co-solvency and Co-nonsolvency are two extreme phenomena in the field of polymer solution. The former is the phenomenon that a mixture of two nonsolvent forms a good solvent for... -
Bacterial lipoteichoic-acid (LTA) micelles: From molecular self-assembly to m...
Whilst the biological effect of lipoteichoic-acid (LTA) contributing to bacterial infections is widely reported in microbiological and immunological studies, very little is... -
Adsorbtion from nematic mixtures: bulk characterization
The aim is to measure any tendency towards phase separation in a nematic mixture to complement an adsorption study on the same mixture. The base is 4-pentyl 4¿- cyanobiphenyl... -
Investigation of membrane polymer complex using SANS
The interaction between lipid vesicles and macromolecules, like polymers is of intense importance from both theoretical and practical point of view. On one hand lipid vesicles... -
Interaction of a pH-sensitive Polymer with a Model Lipid Membrane in the Form...
This SANS experiment was proposed by 4 PhD students from 3 different institutions in a Marie-Curie Training Network. They are all in the second year of their PhD and their... -
Controlled release from lipid-alkylglycoside vesicles, as triggered by amylas...
The consumer demands for functional food have increased the interest for encapsulation of bioactive compounds in the food industry. Encapsulation is crucial, since these... -
pH responsive Core-Shell-Corona (CSC) micellar complexes: Corona- and teleche...
Coacervation is an electrostatically-driven liquid-liquid phase separation process, resulting from the association of oppositely charged macro-ions. In this framework,... -
Using SANS to understand the structural basis for the rheology of molten choc...
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
Using SANS to understand the structural basis for the rheology of molten choc...
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
Radiation induced changes in block copolymer micelles
Block copolymer micelles have been used to encapsulate various chemotherapeutic drugs, which can be delivered to the tumour site using the so-called Enhanced Permeation and... -
Polystyrene latex - 'single crystal' structure studies and melting under flow
For deionised, charge stabilised latices, there has been some uncertainty about the stacking sequence of close packed layers in samples at equilibrium. The ABCA stacking in... -
Architecture of lipid-protein nanoglobules in velvet worm prey capture slime
Fiber fabrication in animals is an important inspiration source for polymeric materials. Velvet worm prey capture slime represents a unique way of fiber fabrication by using... -
Using SANS2D to resolve the opening of MscL clusters in proteoliposomes in re...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the... -
SANS Investigation into the Mode of Interaction between Antibiotics and Diffe...
In this part of proposed work, we wish to explore how antibiotics minocycline and tetracycline interact with model lipid bilayers in the form of SUVs, mimicking key features of... -
A SANS study of nano-gels with a temperature tunable bio-interface
Hyaluronic acid (HA) plays a key role in tumour cell bio-adhesion and, as such, this interaction opens up possibilities for targeted tumour pathologies We have created a...
