22 datasets found

Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with...

Understanding how drugs interact with physiologically relevant environments is crucial for the future of effective drug design. An important class of potential drugs are central...

This proposal continues our work into surfactant templated films formed from surfactant/polyelectrolyte solutions. Recently we have been studying the encapsulation of...

Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using...

Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our...

As a new group of synthetic biosurfactants, the acyl-L-carnitines offer potential for different applications including working as edible biocides. Whilst extensive studies have...

Results from this experiment will help develop to design 21st century surfactants (better performance with lower environmental consequences) by gaining essential information on...

This experiment will use high resolution neutron diffraction to investigate the crystal and magnetic structure of the cobalt adipate framework, Co(CO2(CH2)4CO2), at lower...

We will exploit the unique capability of Nimrod in the study of the long standing issue of polymer crystallisation. We focus on isotactic polypropylene which has been quenched...

The exceptional high temperature mechanical properties of Ni-base superalloys has resulted in their widespread use in high temperature applications. These alloys conventionally...

Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular...

The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of...

Here we propose to look at the structure of two phosphocholine lipids, and their larger scale structures in aqueous solution. Depending on the length of the fatty acid chain in...

This proposal aims to extend our understanding of ionic liquid structure and determine the effect of a short and long alkyl chain length ionic liquid on the nanoscale...

Partially oxidised cellulose nanofibrils have recently been found to form gels in the presence of small amounts of salt or surfactant. As cellulose is a renewable, sustainable...

The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving...

We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the...

This proposal is part of a new project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils with small amounts of salt or...

Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using...

Solid oral dosage forms consist of polymer layer encapsulated drug-bound particles with a desired drug release profile e.g. pulsatile, controlled, delayed and targeted,...