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CuH: a (nearly) 200 year old problem SANDALS
Copper (I) hydride, CuH, is unique amongst the binary metal hydrides in that it can be synthesised, at room temperature, in aqueous solution. In recent years CuH generated in... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
Polymer displacement by surfactant at colloidal interface
The interactions of neutral polymers with surfactants have a key role in detergency and are systems of current academic and commercial interest. Here, we propose to study the... -
pH-Responsive Polyelectrolyte Brushes Studied by Neutron Reflectivity and in ...
pH-responsive polymer brushes comprise of long polymer chains of either a weak acid or base chemically attached to a surface. Depending upon the degree of ionisation along the... -
The interaction of novel gold supraparticles with model lipid membranes
Engineered nanoparticles (NPs) found large application in medicine as theranostic materials for the diagnosis and therapy of many diseases. The understanding of the interactions... -
Shear Stability of Emulsions in the Presence of Co-Surfactants with Various C...
High internal phase aqueous-in-oil emulsions prepared by oil-soluble polyisobutylenesuccinicanhydride (PIBSA) with a water-soluble co-surfactant n-alkylpolyacrylamide (PAM)... -
Using the nano discs approach at surfaces to determine the relation between s...
Membrane bound proteins continue to be to date the most elusive molecules in nature, since they are only functional in the lipid bilayer. We have developed a method to study... -
Small Angle Neutron Scattering Study of the Adsorption of Amine ¿functionalis...
Amine-functionalised poly(alkylene oxides) are used extensively as swelling inhibitors in water-based drilling fluids. This study will broaden our understanding of the mechanism... -
Simultaneous Raman and INS studies of high energy excitations in C70
The vibrational spectrum of C70 has been investigated by many techniques since it became available in significcant quantities. Previous INS spectra were recorded with small... -
Composition dependent structure in mixtures of water and hydrogen bonded mono...
This is part of a project concerning the interplay between water and other H-bonded liquids using a range of complementary experimental techniques, e.g. dielectric spectroscopy,... -
Startup and Calibration
This dataset has no description
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Assembling floating, very sparsely tethered, protein-lipid bilayers.
We have recently used Polref in to measure the assembly of tethered floating lipid bilayers. These are useful models of biological membranes in which a phospholipid bilayer is... -
Structural investigations of low-temperature "trapped solutions" of C60 fulle...
We propose a series of neutron scattering measurement to determine the water structure in amorphous H2O/C60 fullerene vapour deposits. We believe that these samples, prepared by... -
pH Responsive Polymer Blend Surfaces
Polymers, end-functionalised with carboxylic acid (COOH) groups do not normally segregate to film surfaces due to the high surface energy of these functionalities. However, we... -
Swelling of Single Supported Bilayers ¿ First Systematic Investigation of the...
This proposal addresses bilayer swelling experiements on floating supported bilayers (FSBs) in the presence of biological buffers. Previous work on multilamellar vesicles has... -
Spontaneous surface multilayer formation in oligoamine ¿ surfactant mixtures
This proposal is part of a major EPSRC (EP/GR065705)/Unilever funded programme to develop and control the spontaneous formation of surfactant multilayer structures at... -
Tuneable Adsorption of Soft Colloids on Model Biomembrane
Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their... -
Oxidation of gram-negative cell-wall proxy with OH radicals - kinetics and me...
Hydroxyl radicals may be used as disinfection agent in the advanced oxidation processes or tertiary treatment of waste and occasionally drinking water. We very recently oxidised... -
Interplay of apoptosis regulating Bcl-2 proteins with mitochondrial membranes...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Structure of the myoglobin-trehalose-water system
In this proposal we will study the structure of the myoglobin-trehalose-water system. It is well known that trehalose has an excellent cryo- and bioprotective role for...
