152 datasets found

Gold provides a high quality surface on which to arrange biomolecules such as proteins since we can use cysteine amino acids to deliver gold thiol chemical bonds which can...

Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element...

Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...

Recently the intracellular domain (ICD ) of the Na+/H+ exchanger isoform 1 (NHE1), is a transmembrane protein, has been identified as an intrinsically disordered protein....

The recent experimental verification of the unique odd-frequency spin triplet superconductivity in artificial thin film ferromagnetic-superconducting structures is likely to...

This proposal constitutes part of our ongoing study towards understanding how collagen based polypeptides interact with ionic surfactants using SANS. Both SDS and C12TAB will be...

Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),...

The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs...

We wish to determine the effect of various stabilisers on anisotropic pigment particles that are being developed for use in liquid crystal composites. We will investigate the...

Asphaltenes are a complex and problematic fraction of crude oil that can precipitate, alter wettability and stabilise unwanted oil-in-water emulsions. Asphaltenes have a high...

One of the major challenges in the fight against antimicrobial resistance is the development of antimicrobial compounds that selectively disrupt bacterial membranes and leave...

Bacterial and fungal infections of cereal crops pose a considerable risk to global food security. Typically plant pathogens are controlled through the use of chemical agents...

Halogen bonding is a directional intermolecular interaction that occurs between covalently bonded halogens and Lewis bases. It is caused by the anisotropic distribution of...

Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by...

The overall objective is to model the amount and composition of adsorbed mixtures of three types of zwitterionic surfactant and two charged surfactants at the silica/water...

Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the...

The bacterial cell envelope is one of the best targets in antimicrobial development. This proposal focuses on understanding how lipids move between the membranes of the...

The formation of water containing crystal forms, so-called hydrates, is a real problem for the pharmaceutical industry. Hydrates show thermodynamically the lowest solubility in...

This proposal is part of a broad programme of collaborative research between RAL / Oxford and Unilever, using predominantly scattering techniques to investigate the nature of...

Pseudoelastic Co-Ni-Ga high-temperature shape memory alloys are characterized by a wide range of tunable transformation temperatures and lower processing costs compared to...