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Phase diagram of LAS molecule: SANS investigation into surfactant and lipid m...
This proposal would like SANS time to better understand the LAS phase diagram. This has been prompted by recent experiments which show the system is not fully understood under... -
Structure and formation kinetics of insulin aggregates
We will use time-resolved SANS measurements to follow the self-assembly kinetics of insulin from protein monomers to fibrils. By measuring through a well-defined lag phase we... -
Controlling the length of polymeric supramolecular nanotubes
The self-assembly of (cyclic peptide)-polymer conjugates provide a versatile and functional platform for the precise design of polymeric supramolecular nanotubes. Moving the... -
Controlled release from lipid-alkylglycoside vesicles, as triggered by amylas...
The consumer demands for functional food have increased the interest for encapsulation of bioactive compounds in the food industry. Encapsulation is crucial, since these... -
Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR... -
Co-adsorption of eggshell membrane polypeptide-surfactant mixtures at oil-in-...
An eggshell membrane polypeptide is highly surface active and effective at emulsion stabilization. We explore how to use SANS to study the interfacial layers surrounding the... -
Asymmetric diffusion of water into bicontinuous cubic lipid nanomaterials usi...
In this proposal we will investigate hypothesized asymmetric diffusion of water into lipid cubic (QII) phases. This asymmetric diffusion, which is relevant to the behavior of... -
Effect of serum and electrolyte on the structure of nanoemulsions intended fo...
Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as... -
The competition between two polymers for adsorption onto one surface
The behaviour of multiple polymers in competition for colloidal silica has previously been investigated in our group using solvent relaxation nuclear magnetic resonance. We... -
Using contrast matching to understand the networks in multicomponent systems
We have been focusing on two component gel networks. Here, both components can individually form gels. In a mixed system, the LMWG can either co-assemble or self-sort. In a... -
Surfactant induced gelation of TEMPO-oxidized cellulose; Using betaine-based ...
Our group has been working cellulose nanofibrils (OCNF) which form hydrogels in the presence of certain additives. Previously, we have studied the effect of salt, single... -
Cellulose-based polyelectrolytes for microencapsulation: conformational trans...
Addition of multivalent salts to water soluble polyelectrolytes, such as sodium carboxymethyl cellulose (NaCMC), induces conformational change to the polyelectrolyte structure,... -
Conformations in partially mixed block copolymers of partially deuterated pol...
Nascent 'disentangled' block copolymers of Ultra-high Molecular Weight Polyethylene (UHMWPE) with a reduced number of entanglements were synthesized having protonated (hPE) and... -
Aggregation of random co-polymers
This proposal builds upon the successful study of a cationic copolymer capable of forming polymer micellar-like aggregates, simply by reducing pH (D33 at ILL 9-12-433 see... -
Developing a general approach to resolution of accessory proteins bound to cl...
Endocytosis plays a central role in allowing the selective transport of molecules, via membrane-derived vesicles, into cells. Vesicle formation is controlled by a complex... -
Unravel Stabilization Mechanism of CO2 Foams under High Temperature and High ...
Long-term stable CO2 foams were generated under high temperature (120 ºC) and high pressure (12 MPa) (HPHT) in our laboratory using a C22-tailed weak cationic surfactant,... -
Chain exchange mechanism of complex coacervate core micelles
Complex coacervates have been studied for a long time for their medical applications and unusual physical-chemical properties: they are dense networks of poly-electrolytes, that... -
Kinetics of amphotericin B interaction with model human and fungal cell membr...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of... -
SANS Contrast Matching Studies of Radiation-grafted Anion-exchange Membranes
We request two days beam time on SANS2D for the study of radiation-grafted anion-exchange membranes, both dry and hydrated under different ratios of D2O/H2O. These materials... -
Are hydrotropes a unique class of solutes?
The aim is to improve understanding of solution properties and aggregation of hydrotropes and alkyl¿hydrotropes, and the relationship with common surfactants. Although they are...
