Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as vehicles for the delivery of poorly-water soluble drugs. We have recently developed a series of novel nanoemulsions containing either trilaurin or soybean oil as the disperse phase and stabilised by the non-ionic surfactant, oleyl polyoxethylene (10) ether. In order to use the NE as vehicles for the delivery of cancer it is essential to understand the effect of electrolyte and plasma proteins on the structure of the NE. The proposed SANS study will therefore determine the effect of electrolyte and plasma proteins on the properties of the NE. The insight provided by the study should provide a better understanding of the potential of NE as vehicles for drug delivery.