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Formulating polymer solutions to stabilise polymeric foams
Polyurethane foams (PUF) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agents... -
The high-pressure structures of carbon dioxide hydrate
The gas hydrates offer potential as hydrogen and carbon dioxide storage materials for use either in transport applications or for carbon sequestration. We have discovered a... -
Adsorption of liquid crystal nanostructured particles to model hydrophilic an...
Cubosomes and hexosomes are particles with internal liquid crystal structures of the bicontinuous cubic or reverse hexagonal nanostructures respectively. The nanostructure... -
Can surfactants be pushed out of polymer layers by applying compression?
For many applications such as paints, foods and drug formulations, aggregation of colloidal particles is prevented by combining polymer and surfactant adsorption. Key to this... -
Amide monolayers at the polymer melt air interface
This proposal seeks to identify and characterise the adsorption of primary linear amides that adsorb to the surface from the bulk of a polymer melt. These layers are... -
Amino-Acid Based Surfactant Monolayers on a Range of Subphases
Amino acid based surfactants have been known for many years but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from... -
Simultaneous SANS and modulated SESANS for studies of surfactant templating o...
In the previous round we trialled use of the new techniques enabled on Larmor which permit simultaneous measurements of nanoscale and macroscale structure. These experiments... -
The effect of particles on the structure of mucin ¿ understanding the challen...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
The hydration and ordering of lamellar block copolymer films prior to the for...
The key to the use of polymer vesicles as effective molecular delivery systems is in the ability to efficiently encapsulate a molecular payload within the vesicle. We would like... -
Iron Oxide Nanoparticle Interactions with Lipid Bilayers in a Magnetic Field
Iron oxide nanoparticles are one of the first nanomaterials to be approved for use in the body. However, research into particle binding and incorporation to, as well as... -
Neutron reflectivity study of bacterial lipopolysaccharide interactions with ...
Bacterial LPS (endotoxin) is a key determinant of host/pathogen interactions. We propose to investigate the role of membrane lateral phase separation on LPS insertion into model... -
Determining the Structure of Simple Stratum Corneum Lipid Models for Drug Del...
Using a simple model we wish to mimic the lipid structure of the stratum corneum (the top layer of the skin). The simple model offers several advantages to our research area... -
Water-based gels of half N-acetylated chitosans; potential pharmaceutical exc...
These experiments are part of a much broader programme at the University of Reading. focused on the use of water-soluble half-acetylated chitosan as a mucoadhesive polymer,... -
Opening up microemulsion phases in CO2
New types of water-in-CO2 microemulsions using mixed surfactant systems will be investigated by high-pressure SANS (HP-SANS). Exciting new results (see report on RB820030) have... -
Using SANS2D to resolve the opening of MscL clusters in proteoliposomes in re...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the... -
Dynamics of Poly Dimethyl Amino Ethyl Methacrylate / water glycerol mixtures
We want to study the microscopic mechanisms of solvent dynamics such as water and glycerol in ahydrophilic polymer. Dielectric measurements suggest that below the glass... -
The influence of transmembrane potential on the orientation of antimicrobial ...
Natural antimicrobials are of great interest, since they are antibiotics that act on the biological membrane, and it is believed that this makes it far more difficult for... -
Controlling the morphology of fullerene-free polymer solar cells using additi...
We have recently demonstrated, using small angle neutron scattering in combination with other techniques, that in organic photovoltaic devices (OPVs) the additive... -
SANS Study of the interaction of reconstituted model wheat waxes with non-ion...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Surface structures of polycations in confined geometries
A second-generation surface force style apparatus has been developed to probe the inter-surface and near-surface structures under compressive forces. Systems of current academic...