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Using small angle neutron diffraction to describe the status of water in solu...
Fish oocytes and embryos are complex cryobiological objects for which, successful cryopreservation has still not been achieved. This circumstance seriously restricts the... -
Insight into the atomic and intermediate level structure of spherical and rod...
Here we propose to look at the structure of two phosphocholine lipids, and their larger scale structures in aqueous solution. Depending on the length of the fatty acid chain in... -
Effect of Polymer Architecture on Solution Interactions with CTAB/SDS micelles
Dr Edler¿s group has recently been studying the interactions between polymers and surfactant micelles in solution in order to understand how this drives film formation at the... -
Encapsulation of monomers in cationic surfactant-polymer solutions
We have been studying the solution interactions leading to formation of solid polymer-surfactant films at the air-solution interface. We wish to use the mesostructures in the... -
The effect of particles on the structure of mucin ¿ understanding the challen...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Switchable adhesion between oppositely charged polyelectrolytes: dependence o...
Tuning the interactions between different surfaces has technological benefits in areas such as adhesion, compatibilisation and nano-actuators. We shall study the interaction... -
Investigation Into The Mechanism Of Protection Of Proteins During Freeze-Drying
Protection of biological molecules during freezing and lyophilisation is of commercial importance to the pharmaceutical, medical, and food industries. Sugars and surfactants... -
Liquid-liquid immiscibility and glass transitions in aqueous solutions
The microscopic structure of a dilute solution of LiCl in water is determined at different thermodynamic states in both the liquid and glassy phases. This solution exhibits... -
Crystallization of clathrate hydrates from amorphous THF-water solutions
Understanding clathrate hydrate formation and stability is an urgent issue due to their environmental importance. However, a fundamental understanding of the molecular processes... -
Polymer adsorption from fluorinated media in polymer stabilised drug suspensions
The formation of stable particle dispersions are essential to the success of a wide range of commercial products from inks, paints and foodstuffs to cosmetic and pharmaceutical... -
Encapsulation of hydrophobic species into cat-anionic micelles in polymer sol...
This proposal continues our investigations into film forming polyelectrolyte-surfactant solutions. We have found that mixed cat-anionic micelle systems offer greater control... -
Surface structures of polycations in confined geometries
A second-generation surface force style apparatus has been developed to probe the inter-surface and near-surface structures under compressive forces. Systems of current academic... -
Understanding drug carrier interactions in the stomach
In a pharmaceutical industry context, hydrophilic polymeric matrices are a popular methodology for extending the release of drugs. However, issues sometimes arise -... -
Validating calorimetric self aggregation models: Self aggregation of cationic...
Ligand self aggregation is a common problem when studying interactions with bio(macro)molecules. In particular for techniques requiring relatively high ligand concentrations,... -
Response of PAN-pyrene-micelle based sensors to metal ions
We have been studying the solution interactions leading to formation of solid polymer-surfactant films at the air-solution interface. We want to use the mesostructures in the... -
Large Scale Structure in CTAB/SDS-Polymer Solutions
This proposal continues our investigations into polyelectrolyte-surfactant solutions which form films at the air-solution interface. We have found that solutions of mixed... -
Microscopic structure of acetic acid in water and methanol
Some of the most important chemical reactions involve Brønsted acids and bases where the solvation structure and transport dynamics of charged defects in hydrogen-bonded... -
Effect of Aging Temperature on Inorganic Films Templated by Polymer-Surfactan...
Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the... -
Curvature effects in polyelectrolyte-surfactant solution interactions
This proposal continues our investigations into polyelectrolyte-surfactant solutions which form thin films at the air-solution interface. Our previous work has investigated the... -
Characterization of P3HT:PCBM blends by SANS measurements
Blends of poly-3-hexyl-thiophene (P3HT) and 6,6-phenyl-C61 butyric acid methyl ester (PCBM) are the most promising candidates for active layers of plastic solar cells with high...