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The effect of alcohol chain length on the interaction between PS-PEO copolyme...
In many applications, surfactants are formulated with a variety of additives to achieve a desired range of properties; polymers and cosurfactants/cosolvents (such as alcohols)... -
Anion effects on self-assembly in deep eutectic solvents.
Deep Eutectic Solvents (DES) are mixtures of an organic salt with a hydrogen bond donor that form strong interactions which hinder crystallisation. DES share many features with... -
Structural origin of anomalous relaxation behaviour in alcohol-water mixtures
In recent dielectric and calorimetric studies of some alcohol-water mixtures we have discovered unexpected and unexplained relaxation behaviours. Our aim with this proposal is... -
Curvature effects in polyelectrolyte-surfactant solution interactions
This proposal continues our investigations into polyelectrolyte-surfactant solutions which form thin films at the air-solution interface. Our previous work has investigated the... -
Temperature and flow stability of model sodium alkylbenzene sulfonate (NaLAS)...
Linear sodium alkylbenzene sulfonate (NaLAS) is one of the most extensively used anionic surfactant in the world, mainly as a biodegradable laundry detergent, with an annual... -
Nanosuspsomicroemulsions: nanosuspension stabilty
At Kings College London we have recently developed a novel combination formulation, a nanosuspsomicroemulsion (NSME), comprising of a microemulsion (ME) containing one drug and... -
New surfactants forming anisotropic micelles and microemulsions in CO2
An analogue of the popular surfactant AOT with isopropyl glycol tails (IG-AOT, Figure.1) has been recently designed as a co-surfactant for water-in-CO2 (w/c) systems: stable... -
Mechanism and rates of phospholipid exchange and flip-flop under physiologica...
Variation in lipid composition between different biological membrane and across membranes are vital for a wide range of cellular functions. Significant differences in lipid... -
AGGREGATION BEHAVIOUR OF A NOVEL P-AOT SURFACTANT
This proposal aims to provide essential surfactant micellisation structural information of significant interest in its own right but also as key information for our on-going... -
Kinetic Study of the Mechanistic Complexation Process Between DNA and Cationi...
We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing... -
Protein-decorated superparamagnetic iron oxide nanoparticles
The aim of this research is to understand the structural confirmation of dextran coated iron oxide (Fe3O4) nanoparticles in the presence of Bovine serum albumin (BSA) in aqueous... -
Gelatin scaffolds from marine species: Physical gels and enzymatically cross-...
Hydrogels from biopolymers are attracting increasing attention for a range of biomedical applications, but the lack of structural understanding hinders the development of new... -
Constructing analogues of gemini and oligomeric surfactants through noncovale...
Gemini-like and oligomeric-like surfactants can be constructed by single-chain or gemini surfacants with connecting molecules through noncovalent binding without complicated... -
Mixed micelles with green surfactants
This proposal aims to explore aqueous phase structures and compositions of a series of mixed surfactants. Although standard petrochemically-derived surfactant mixtures have been... -
interaction of a pharmaceutical water-soluble polymer with bio-relevant surfa...
We have been developing hydroxypropylmethyl cellulose (HPMC) microspheres for delivering poorly water-soluble drugs. The in vitro dissolution data showed that the presence of... -
Solution aggregation of short peptide amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
The effect of unsaturation on the shear dependence of cationic lamellar phase...
Products such as fabric and hair conditioners are commonly in the form of di-alkyl chain cationic lamellar phase dispersion. The effects of shear on such lamellar phase... -
Rhamnolipids and Amphotericin B: a potential highly specific delivery system ...
Rhamnolipids are a type of glycolipid biosurfactant, produced as secondary metabolites by various Pseudomonas and Burkholderia species; they have been shown to possess... -
AOT stabilized aqueous ferrofluids
The aim of the experiment is to employ SANS to study the physical properties of a novel and very stable aqueous Fe3O4 ferrofluid system stabilized by the commercially available... -
Characterisation and peptide resistance capabilities of bacterial membrane mi...
Lysylphosphatidylglycerol (LPG) is a major constituent of the plasma membrane of the bacterial pathogen methicilin resistant Staphylococcus aureus (MRSA), which has been...
