42 datasets found

This database has been designed to meet the growing need to identify fluorophore contaminants in environmental matrices. It gathers spectral fingerprints for 108 fluorescent...

At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of...

Combining structural information about silk proteins in solution whilst undergoing mechanical shear will open a new window into silk production in vivo and provide valuable...

Protein-lipid\membrane interactions are fundamentally important to biological processes. We have examined the role protein hydrophobicity in protein-membrane interactions...

Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...

Bio-responsive polymers hold great promise as delivery vehicles for drugs, peptides and proteins as their chemistry can be tuned to effect a change in physico-chemical...

We wish to investigate the pH-dependence of the strong interfacial interaction of 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) with poly(silicic) acid at the air-water...

Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds...

The presence of a monolayer of surfactant material at the air-water interface of the lung is crucial for respiratory function. It is well known that exposure to the ubiquitous...

IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier...

Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element...

Organisms which live in the presence of large quantities of salt are known as halophilic (meaningsalt-loving). Halophilic proteins are of great interest due to their ability to...

The surface tension of proteins often exhibits a reproducible lagtime, which is sensitiv to a range of conditions such as concentration, pH, ionic strength. We have also found...

Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds...

Oligo(ethylene glycol) self-assembled monolayers (SAMs) effectively prevent the adsorption of proteins from biological media. Despite the importance of this effect for...

We are unravelling the solution structures of the Fab and Fc fragments in the IgA antibody family important in mucosal immunology. Having completed the structures for IgA...

Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large...

Adsorption of proteins at all surfaces has a characteristic lagtime which can be monitored by surface tension at the air/water interface. The cause of the lagtime is not...

The myelin sheath is a multilayered membrane wrapped around axons in the vertebrate nervous system; it enables the rapid transmission of nerve impulses. It contains a set of...

Proteins from Moringa trees have attracted considerable interest as flocculents for water purification and possibly as materials for remediation of contaminated soil....