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New Approaches to Producing Floating Supported Bilayers
The complex sample environment needed for floating supported bilayers has often led to a need to constantly redevelop the system to improve reproducibility. Here we plan to... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
A study of the role of divalent cations in the stability of smooth LPS in out...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaires disease. It is important as; a barrier to antibiotics & the site of... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Incorporating outer membrane proteins in outer membrane models
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Introducing the O-antigen into Bacterial Outer Membrane Models
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Assembling Biomimetic layers on monolayers of Gold Nanoparticles
Gold provides a high quality surface on which to arrange biomolecules such as proteins since we can use cysteine amino acids to deliver gold thiol chemical bonds which can... -
A complex model of the bacterial outer membrane containing oriented proteins ...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaire?s disease. It is important as; a barrier to antibiotics & the site of... -
Repeat of Assembling floating, very sparsely tethered, protein-lipid bilayers.
This was granted 2 days but problems with our samples meant that no data was got. After successful practice on Biacore offline, failure was due to using a new (faulty) batch of... -
Comparative Interaction Studies of Antimicrobial Agents on Floating Asymmetri...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
The Interactions of Blood Components with Models of the Gram Negative Bacteri...
One of the major challenges in the fight against antimicrobial resistance is the development of antimicrobial compounds that selectively disrupt bacterial membranes and leave... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
New Approaches to Producing Floating Supported Bilayers
The complex sample environment needed for floating supported bilayers has often led to a need to constantly redevelop the system to improve reproducibility. Here we plan to... -
Antibiotic paths through the bacterial outer membrane: The strange case of va...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
The Effect of Core Oligosaccharide Size on the Binding of Antimicrobial Prote...
This dataset has no description
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Comparative Interaction Studies of Antimicrobial Agents on Floating Asymmetri...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
Repeat of Assembling floating, very sparsely tethered, protein-lipid bilayers.
This was granted 2 days but problems with our samples meant that no data was got. After successful practice on Biacore offline, failure was due to using a new (faulty) batch of...
