New Approaches to Producing Floating Supported Bilayers

DOI

The complex sample environment needed for floating supported bilayers has often led to a need to constantly redevelop the system to improve reproducibility. Here we plan to examine the fabrication of floating supported bilayers below two differing grafted Self assembled monolayers; namely (15-Mercaptopentadecyl)-1-aminoethanol (SH(CH2)15CONHC2H4OH) and diothiol-dilaurylphosphatidylcholine (2SH-DLPC). The two SAM will be examined with and with free floating DPPC and then dDPPC/RaLPS bilayers. If successful the use of these relatively inexpensive and stable thiols should enhance our ability to produce realistic bio-mimetic membrane systems for the neutron reflection community.

Identifier
DOI https://doi.org/10.5286/ISIS.E.92923983
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/92923983
Provenance
Creator Dr Nico Paracini; Professor Jeremy Lakey; Dr Andrew Caruana; Dr Arwel Hughes; Dr Martynas Gavutis; Dr Luke Clifton
Publisher ISIS Neutron and Muon Source
Publication Year 2021
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2018-04-23T07:30:00Z
Temporal Coverage End 2018-04-26T08:25:18Z