37 datasets found

Organogelators are small molecules that self-associate into extensive network structures. Our interest lies in a homologous series of such gelators, the...

This experiment will provide key information on the solution behaviour of novel polymer constructs designed as drug-delivery vectors. Is is known that solution behaviour of many...

Previous SANS studies of anti-cancer polymer-drug conjugates (PDCs) (HPMA-Doxorubicin) identified a correlation between conjugate solution conformation and clinical results. The...

Recurring infection following dental interventions such as fillings is the most common reason for failure, leading to further treatments including root canal therapy, where the...

Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions...

Novel self-assembling di-block polymers have been designed multi-component polymer-drug conjugates for the delivery of cytotoxic drugs to solid tumours. It is known that the...

Bio-responsive polymers hold great promise as delivery vehicles for drugs, peptides and proteins as their chemistry can be tuned to effect a change in physico-chemical...

The controlled synthesis of precious metal nanoparticles of the appriopriate chemical composition, optimised size and morphology for use in catalysis is an ongoing experimental...

Phase behaviour studies have identified hydrogen bonding as a key aspect in polymer solubility in fluorinated liquids, both in terms of solute-solvent and solute-solute...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

Nuclear power has played an important role in Britain¿s history and is set to play an equally important role in its future. We have recently established a network involving...

Recurring infection following dental interventions such as fillings is the most common reason for failure, leading to further treatments including root canal therapy, where the...

Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for...

Polymer therapeutic describes polymeric drugs, polymer-drug conjugates, polymer-protein conjugates, polymeric micelles to which drug is covalently bound, and multicomponent...

Nuclear power at present is the only viable option for long-term power generation in the UK and as such the easy incorporation of the fission product 90Sr into the biosphere...

Incorporation of d- or f-block metals into ligand systems that renders a metal complex surface active or drives its partitioning into surfactant phases enables the localisation...

Incorporation of d- or f-block metals into ligand systems that renders a metal complex surface active or drives its partitioning into surfactant phases enables the localisation...

Incorporation of d- or f-block metals into ligand systems that renders a metal complex surface active or drives its partitioning into surfactant phases enables the localisation...

Gels formed by mixtures of partially fluorinated surfactants, water and oil have been identified and are under investigation to identify the gelation mechanism. Preliminary SANS...

Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions...